LONG-TERM RESULTS OF OPERATION FOR NON-SMALL-CELL LUNG-CANCER IN THE ELDERLY

LONG-TERM RESULTS OF OPERATION FOR NON-SMALL-CELL LUNG-CANCER IN THE ELDERLY
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DOI:
10.1016/0003-4975(90)91119-v
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发表时间:
1990-12-01
影响因子:
4.6
通讯作者:
SUGIMACHI, K
SUGIMACHI, K
中科院分区:
医学2区
文献类型:
--
作者:
ISHIDA, T;YOKOYAMA, H;SUGIMACHI, K

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我们手术治疗了185例70岁或以上的非小细胞肺癌患者。手术死亡率为3%,5年生存率为48%。死亡率和预后与年轻患者相似。大量吸烟或有呼吸缺陷的老年患者的数量很高,但肺切除术的发生率很低。在组织学类型方面没有基于年龄的差异。TNM分类和可治愈性。肺部并发症发生在21%的老年患者,与术前肺功能和吸烟习惯有关。老年人肺癌择期行肺切除术时,术前应全面评估肺功能,术前术后应给予物理治疗。如果预测术后肺功能低于0.8 L/m2肺活量和0.6 L/m2 1秒用力呼气量,应考虑有限切除或非手术治疗。
We surgically treated 185 patients with non-small cell lung cancer who were 70 years old or older. The operative mortality rate was 3%, and the 5-year survial rate was 48%. The mortality and prognosis were similar to those in younger patients. The number of elderly patients who smoked heavily or who had ventilatory defects was high, but the incidence of pneumonectomy was low. There were no differences based on age in regard to histological type. TNM classification, and curability. Pulmonary complications occurred in 21% of the elderly patients and were correlated with preoperative pulmonary function and smoking habits. When the elderly are to undergo elective pulmonary resection for lung cancer, the preoperative evaluation of pulmonary fuction should be thorough, and both preoperative and postoperative physical therapy should be given. If postoperative pulmonary function is predicted to be less than 0.8 L/m2 of vital capacity and 0.6 L/m2 of forced expiratory volume in 1 second, a limited resection or nonsurgical therapy should be considered.