Pathological characteristics of esophageal cancer.
Pathological characteristics of esophageal cancer.
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食管癌的病理特征。
DOI：
10.3892/ol.2014.2223
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发表时间：
2014-08
期刊：
影响因子：
2.9
通讯作者：
Liu ML
中科院分区：
文献类型：
--
作者：
Shi HY;Zhu SC;Shen WB;Liu ML
利用大型病理切片研究了食管鳞状细胞癌的病理特征，包括经常发生的多发性致癌病变（ML）、严重不典型增生（SD）和直接壁内浸润（DI）。共有52例食管癌患者接受了手术切除，并被诊断为食管鳞状细胞癌。然后将手术切除标本制成大切片进行病理检查。癌的实际长度是在手术期间根据显微镜确定的长度计算的。对大切片进行显微镜病理检查，鉴定ML、SD、DI，并进行统计分析。不同检查方法得到的病变长度各不相同。分别有 15 名、28 名和 41 名患者出现 ML、SD 和 DI。此外，在有淋巴浸润或疾病晚期的患者中，DI 的发生率较高。 ML、SD和DI被认为是食管鳞癌的特征，并且ML和DI被发现与淋巴浸润相关。
The pathological characteristics of esophageal squamous cell carcinoma, which include regularly occurring multiple carcinogenic lesions (MLs), severe dysplasia (SD) and direct intramural infiltration (DI), were investigated using large pathological sections. A total of 52 esophageal cancer patients underwent surgical resection and were diagnosed with esophageal squamous cell carcinoma. Large sections of the surgical resection specimens were then made for pathological examination. The actual length of the carcinoma was calculated during surgery from the length determined microscopically. ML, SD and DI were identified during pathological examination of the large sections by microscope and were statistically analyzed. The lesion lengths obtained by the various inspection methods differed from each other. ML, SD and DI were identified in 15, 28 and 41 patients, respectively. Furthermore, a higher incidence of DI was observed in patients with lymphatic infiltration or those with a later stage of disease. ML, SD and DI were identified as characteristics of esophageal squamous cell carcinoma, and ML and DI were found to correlate with lymphatic infiltration.
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