The effect of maternal hemoglobin concentration on fetal birth weight according to trimesters
The effect of maternal hemoglobin concentration on fetal birth weight according to trimesters
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DOI：
10.3109/14767058.2014.979149
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发表时间：
2015-01-01
影响因子：
1.8
通讯作者：
Bakacak, Zeyneb
中科院分区：
文献类型：
--
作者：
Bakacak, Murat;Avci, Fazil;Bakacak, Zeyneb
目的：探讨胎儿出生体重和母亲血红蛋白浓度之间的关系，在不同的trimesters.Methods：这项前瞻性横断面研究包括329名妇女，监测和2013年1月至2014年1月在我们的诊所。记录所有妊娠期的血红蛋白浓度和新生儿的所有出生体重。结果：胎儿体重与孕早期母体血红蛋白浓度呈正相关（p：0.025），与新生儿出生体重呈正相关（p：0.001）。未发现胎儿体重与中晚期血红蛋白浓度之间存在相关性（分别为p = 0.287，p = 0.298）。当独立因素对胎儿体重的影响进行了调查，它被确定为出生周和第一个三个月的血红蛋白水平的影响最大的因素。结论：低血红蛋白浓度在妊娠的第一个三个月似乎与低胎儿出生体重。贫血可直接导致子宫内胎儿生长不良，这是由于胎盘组织的氧气流量不足，或者它可以是母体营养缺乏的间接指标。在这两种情况下，这项研究表明，在怀孕前和怀孕早期治疗贫血与更好的胎儿结局直接相关。
Objective: To investigate the relationship between fetal birth weight and maternal hemoglobin concentrations in different trimesters.Methods: This prospective cross-sectional study comprised 329 women, monitored and delivered between January 2013 and January 2014 in our clinic. Hemoglobin concentrations in all trimesters and all birth weights of the newborns were recorded. Comparisons and correlations were made of the maternal hemoglobin concentrations and birth weights in each trimester.Results: A positive correlation was determined between fetal weight and increased first trimester maternal hemoglobin concentration (p: 0.025). No correlation was found between fetal weights and second and third trimester hemoglobin concentrations (p = 0.287, p = 0.298, respectively). When the effect of independent factors on fetal weight was investigated, it was determined that birth week and first trimester hemoglobin levels were the factors of most influence.Conclusions: Low hemoglobin concentrations in the first trimester of gestation seem to be associated with low fetal birth weights. Anemia can directly cause poor in utero fetal growth due to inadequate oxygen flow to the placental tissue or it can be an indirect indicator of maternal nutrition deficiency. In both circumstances, this study reveals that treatment of anemia before and in the early stages of pregnancy is directly correlated with better fetal outcomes.