Stereotaxic radiofrequency surgery of the normal and the abnormal pituitary gland.
Stereotaxic radiofrequency surgery of the normal and the abnormal pituitary gland.
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正常和异常垂体的立体定向射频手术。
DOI：
10.1056/nejm196902202800808
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发表时间：
1969
期刊：
影响因子：
--
通讯作者：
N. Zervas
中科院分区：
文献类型：
--
作者：
N. Zervas
外科医生们一直在寻找一种最有效、安全和无害的手术方法来治疗脑下垂体肿瘤和正常的脑下垂体。我们仔细研究了正常蝶鞍区的解剖结构，并利用这些信息和一些基本的工程技术，改进了经鼻蝶入路入路至垂体的方法。这导致了一种相对无创的立体定向射频手术，与最低的发病率相关。我将描述我们临床工作之前的历史、解剖学和技术方面的考虑，以及在164名接受血管病理性糖尿病视网膜病变和转移性乳房手术的患者中所获得的结果。
SURGEONS have continually sought an operative approach to pituitary tumors and to the normal pituitary gland that would be maximally effective, safe and innocuous. We have examined in detail the anatomy of the normal sella turcica and have used this information with some basic engineering technics to improve the endonasal trans-sphenoidal approach to the pituitary gland. This has resulted in a relatively atraumatic stereotaxic radiofrequency procedure associated with minimal morbidity. I shall describe the historical, anatomical and technical considerations that preceded our clinical work and the results obtained in 164 patients who underwent operation for angiopathic diabetic retinopathy, metastatic breast . . .