Sesquiterpenoids of the drimane class from a sponge of the genus Dysidea.
Sesquiterpenoids of the drimane class from a sponge of the genus Dysidea.
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DOI：
10.1021/np9703297
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发表时间：
1997-11
影响因子：
5.1
通讯作者：
V. Paul;Y. Seo;K. Cho;J. Rho;J. Shin;P. R. Bergquist
中科院分区：
文献类型：
--
作者：
V. Paul;Y. Seo;K. Cho;J. Rho;J. Shin;P. R. Bergquist
从一种未知海绵中分离得到10个倍半萜类化合物，其中7个为新化合物。化合物1-8是补身烷类的倍半萜，而9和10是相同结构类别的12-降倍半萜。新化合物的结构已通过光谱联用方法确定。这些化合物表现出适度的抗菌和酶抑制（Na+/K（+）-ATP酶和PLA 2）活性。
Ten sesquiterpenoids, including seven new ones, have been isolated from an undescribed sponge of the genus Dysidea. Compounds 1-8 are sesquiterpenoids of the drimane class, while 9 and 10 are 12-norsesquiterpenoids of the same structural class. The structures of novel compounds have been determined by combined spectroscopic methods. These compounds exhibited moderate antimicrobial and enzyme inhibitory (Na+/K(+)-ATPase and PLA2) activities.