The roles of perirhinal cortex, postrhinal cortex, and the fornix in memory for objects, contexts, and events in the rat
The roles of perirhinal cortex, postrhinal cortex, and the fornix in memory for objects, contexts, and events in the rat
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DOI：
10.1080/02724990444000203
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发表时间：
2005-07-01
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影响因子：
--
通讯作者：
Eacott, MJ
中科院分区：
文献类型：
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作者：
Eacott, MJ
对内侧颞叶的解剖下结构的调查显示了许多高度相互联系的区域，这导致一些人提出该地区作为单一记忆系统运行。但是，在这里，我们概述了我们实验室的许多研究的结果，这些研究研究了大鼠的周围皮层和后皮层对记忆的贡献，特别集中在它们在对象记忆中的各自作用上。通过将损害和保留能力的模式进行对比，我们建议周围皮层和后皮层对学习和记忆做出独特的贡献：例如，后皮层对于学习娱乐内部位置和上下文而言至关重要。我们还提供了证据表明，尽管这些皮质区域与海马之间具有很强的连通性，但海马，海马，正如Fornix的病变所证明的，它具有其自身构成信息有关对象，位置和上下文的独特功能。
Investigation of the anatomical substructure of the medial temporal lobe has revealed a number of highly interconnected areas, which has led some to propose that the region operates as a unitary memory system. However, here we outline the results of a number of studies from our laboratories, which investigate the contributions of the rat's perirhinal cortex and postrhinal cortex to memory, concentrating particularly on their respective roles in memory for objects. By contrasting patterns of impairment and spared abilities on a number of related tasks, we suggest that perirhinal cortex and postrhinal cortex make distinctive contributions to learning and memory: for example, that postrhinal cortex is important in learning about within-scene position and context. We also provide evidence that despite the strong connectivity between these cortical regions and the hippocampus, the hippocampus, as evidenced by lesions of the fornix, has a distinct function of its own-combining information about objects, positions, and contexts.