Posttraumatic stress disorder and comorbid major depression: Is the correlation an illusion?
Posttraumatic stress disorder and comorbid major depression: Is the correlation an illusion?
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DOI：
10.1016/s0887-6185(97)00047-9
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发表时间：
1998-01-01
影响因子：
10.3
通讯作者：
Taylor, AE
中科院分区：
文献类型：
--
作者：
Blanchard, EB;Buckley, TC;Taylor, AE
我们已经检查了107个机动车事故（MVA）受害者的数据，共病抑郁症的存在是否是重要的临床，以及是否诊断共病抑郁症的阈值应提高，因为创伤后应激障碍（PTSD）和抑郁症之间的症状重叠。在62名MVA受害者中，有33人在MVA后1至4个月符合PTSD标准，其中27人在MVA后发生抑郁症。LISREL 8.12a分析表明，创伤后应激障碍和重性抑郁症是相关的，但独立的，对创伤的反应。与单纯PTSD患者相比，PTSD和抑郁症患者在前6个月的前瞻性随访中主观上更痛苦，遭受更多的主要角色损害，并且更不容易缓解。诊断共病抑郁症的阈值（5或6个抑郁症状与7至9个抑郁症状）对任何“病例”指标都没有重要影响。“（C）1998 Elsevier Science Ltd.
We have examined data from 107 motor-vehicle accident (MVA) victims with regard to whether the presence of comorbid depression is important clinically, and with regard to whether the threshold for diagnosing the comorbid depression should be raised because of symptom overlap between posttraumatic stress disorder (PTSD) and major depression. Of the 62 MVA victims who met the criteria for PTSD 1 to 4 months post-MVA, 33 also met the criteria for major depression, with 27 cases for which the depression occurred post-MVA. A LISREL 8.12a analysis indicates that PTSD and major depression are correlated, but independent, responses to trauma. Those with PTSD and depression are more subjectively distressed, suffer more major role impairment, and remit less readily over the first 6 months of prospective follow-up than those with PTSD alone. The threshold for diagnosing comorbid depression (5 or 6 depressive symptoms versus 7 to 9 depressive symptoms) has no important effects on any of the indicators of "caseness." (C) 1998 Elsevier Science Ltd.