Ionized calcium concentration and outcome in critical illness
Ionized calcium concentration and outcome in critical illness
复制标题
DOI：
10.1097/ccm.0b013e3181ffe23e
复制
发表时间：
2011-02-01
影响因子：
8.8
通讯作者：
Bellomo, Rinaldo
中科院分区：
文献类型：
--
作者：
Egi, Moritoki;Kim, Inbyung;Bellomo, Rinaldo
目的：评估一组异质危重患者中钙离子水平异常与死亡率的关系。设计：回顾性、临床与生化相结合的研究。环境：四个内科/外科联合重症监护病房。患者：7024例成人危重患者队列。干预措施:没有。测量结果和主要结果：我们研究了7024例患者的177,578个电离钙测量值，平均值为1.11 mmol/L（平均每4.5小时测量一次电离钙）。在重症监护病房住院期间报告的未调整的最低和最高电离钙在重症监护病房幸存者和非幸存者之间存在显著差异（p . 391）
Objective: To assess the association of abnormalities of ionized calcium levels with mortality in a heterogeneous cohort of critically ill patients.Design: Retrospective, combined clinical and biochemical study.Setting: Four combined medical/surgical intensive care units.Patients: Cohort of 7,024 adult critically ill patients. Interventions: None.Measurements and Main Results: We studied 177,578 ionized calcium measurements, from 7024 patients, with a mean value of 1.11 mmol/L (ionized calcium measured every 4.5 hrs on average). The unadjusted lowest and highest ionized calcium reported during intensive care unit stay were significantly different between intensive care unit survivors and nonsurvivors (p