EVALUATION OF A SIMPLE TECHNIQUE FOR ABRUPT INTRAVENOUS INJECTION OF RADIOISOTOPE.
EVALUATION OF A SIMPLE TECHNIQUE FOR ABRUPT INTRAVENOUS INJECTION OF RADIOISOTOPE.
复制标题
评估突然静脉注射放射性同位素的简单技术。
DOI：
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发表时间：
1965
期刊：
影响因子：
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通讯作者：
S. Shimizu
中科院分区：
文献类型：
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作者：
W. Oldendorf;M. Kitano;S. Shimizu
血流动力学评估的几种技术需要突然静脉注射标记化合物。这种方法已经被用于测量心输出量的外部监测技术，试图测量冠脉血流量，以及用于评估脑循环的几种技术。随后的突然注射技术尽可能快速地将标记物质沉积到右心，从而将随后通过心肺通道的示踪剂流动降至最低。这份报告的目的是描述这项技术，并对其将示踪剂快速输送到右心的能力进行评估，比简单的快速静脉注射更突然。技术：这项技术在图1中以图表的形式显示。它已经在前面的部分中被描述(1)。受试者的手臂放在略微抬高的臂板上，肘部略微弯曲。手臂只支撑在肘部和一根手指上(图2)。手臂的上半部分自由地保持在支撑病人的垫子上方。一个œ尼龙搭扣·3的血压袖带放在上臂，充气到大约100毫米的水银，前提是这低于收缩的臂动脉压。袖带放置一分钟，导致手臂远端静脉池扩张，并在警报器中静脉血压上升，超过袖带压力。随后将一根25英寸长的针头放在深的前臂静脉中。袖带pressureisfurtherincreaseduntilitsubstantially超过收缩压。因此，手臂远端的循环被切断，静脉池仍处于扩张状态。在手臂循环中断的情况下，示踪剂被注射到肘前静脉，注射速度不会很快，因为充气的袖带完全中断了循环。通过这种方式可以注射多达3毫升的溶液，而不会引起明显的渗出，但我们通常的技术只使用1毫升的生理盐水。
Several techniques for hemodynamic evaluation require an abrupt intra venous injection of a labeled compound. This approach has been used in external monitoring techniques for measuring cardiac output, in attempts to measure coronary blood flow and in several techniques for assessing cerebral circulation. The following abrupt injection technique deposits labeled material as rapidly as possible into the right heart, so that subsequent streaming of tracer by cardiopul monary passage is minimized. It is the purpose of this report to describe the technique and to present an evaluation of its capability to rapidly deliver tracer into the right heart more abruptly than simple rapid intravenous injection. Technique: This technique is shown diagrammatically in Fig. 1. It has been de scribed in part previously (1). The subject's arm is positioned on a slightly elevated armboard with the elbow slightly flexed. The arm is supported only at the elbow and one finger ( Fig. 2). The upper part of the arm is held free above the mat tress supporting the patient. A “Velcro―3 blood pressure cuff is placed on the upper arm and inflated to about 100 mm of mercury, provided that this is below the systolic brachial arterial pressure. The cuff is left in place for one minute, causing a distention of the venous pool in the distal arm and a rise in the venous blood pressurein the distalarm to exceedthe cuffpressure.A 25-gauge,1 inch needleforsubsequentinjection isplaced in a deep antecubitalvein.The cuff pressureisfurtherincreaseduntilitsubstantially exceedsthe systolic pressure. The circulation in the distal arm is thus cut off with the venous pool still in a distended condition. With the arm circulation thus interrupted, the tracer is injected into the antecubital vein.The rateofinjectioneed not be rapid,sincethe circulation is completely interrupted by the inflated cuff. Up to about 3 ml of solution can be injected in this way without causing significant extravasation, but our usual technique utilizes only 1 ml of saline.