Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations.
Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations.
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DOI：
10.1017/ash.2023.163
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Altman, Deena R
中科院分区：
文献类型：
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作者：
Mills, Alexandra G;Dupper, Amy C;Chacko, Kieran I;Alburquerque, Bremy;Nadkarni, Devika;Berbel Caban, Ana;Fox, Lindsey;Gitman, Melissa R;Obla, Ajay;van Bakel, Harm;Altman, Deena R
对25例万古霉素最低抑菌浓度(≥)为2µg/m L的耐甲氧西林金黄色葡萄球菌(MRSA)菌血症患者和391例对照(MIC和2µg/m L)进行了病例对照研究，分析了与万古霉素最低抑菌浓度升高相关的临床特征、治疗和转归。万古霉素MIC升高与基线血液透析、既往MRSA定植和转移性感染相关。
This case–control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 µg/mL and 391 controls (MIC < 2 µg/mL) characterized the clinical characteristics, treatments, and outcomes associated with elevated vancomycin MIC. Elevated vancomycin MIC was associated with baseline hemodialysis, prior MRSA colonization, and metastatic infection.