A novel strategy for functionalizable photoluminescent magnetic nanoparticles
A novel strategy for functionalizable photoluminescent magnetic nanoparticles
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DOI：
10.1088/2053-1591/1/4/045032
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发表时间：
2014-12-01
影响因子：
2.3
通讯作者：
Kim, Chanjoong
中科院分区：
文献类型：
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作者：
Yan, Huan;Sung, Baeckkyoung;Kim, Chanjoong
本研究提出了可功能化的光致发光磁性氧化铁纳米粒子（PLMNPs），通过加热涂覆有非光致发光的亲水性聚（丙烯酸）（PAA），但没有任何附加的光致发光化学品的磁性纳米粒子。PLMNPs的光致发光起源于在加热过程中从PAA聚合物涂层转化的碳纳米点层。有趣的是，PLMNPs比传统的有机染料更耐光。PLMNPs的进一步功能化容易通过与表面上涂层的羧基的偶联反应实现。PLMNPs可以远程加热，通过施加一个交变磁场，由于超顺磁性，并被发现具有良好的加热效率。所有这些优点使得这些纳米颗粒吸引各种生物医学应用，如双模态成像和热疗治疗。
This study presents functionalizable photoluminescent magnetic iron oxide nanoparticles (PLMNPs) produced by heating magnetic nanoparticles coated with non-photoluminescent hydrophilic poly(acrylic acid) (PAA) but without any add-on photoluminescent chemicals. The photoluminescence of PLMNPs is originated from a carbon nanodot layer that is converted from the PAA polymer coating layer during the heating process. Interestingly, PLMNPs are more photostable than conventional organic dyes. Further functionalization of PLMNPs is easily achieved through the coupling reaction with carboxyl groups of the coating layer on the surface. PLMNPs can be remotely heated by applying an alternating magnetic field due to the superparamagnetism, and are found to have good heating efficiency. All these advantages make these nanoparticles appealing for various biomedical applications, such as dual modality imaging and hyperthermia treatment.