Pre-linguistic Vocal Trajectories at 6-18 Months of Age As Early Markers of Autism
Pre-linguistic Vocal Trajectories at 6-18 Months of Age As Early Markers of Autism
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DOI：
10.3389/fpsyg.2016.01595
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发表时间：
2016-10-19
影响因子：
3.8
通讯作者：
Muratori, Filippo
中科院分区：
文献类型：
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作者：
Chericoni, Natasha;Wanderley, Daniele de Brito;Muratori, Filippo
本研究探讨了自闭症谱系障碍(ASD)婴儿在照顾者与婴儿互动过程中的语前发声轨迹。家庭视频来自10名ASD婴儿和10名典型发育期婴儿(TD)，涵盖三个时间段：0-6个月(T1，47个视频序列)、6-12个月(T2，47个视频序列)和12-18个月(T3，48个视频序列)。总共分析了142个视频序列。发声、长时间重复的喃喃自语、双音节的喃喃自语和第一个单词被纵向研究。此外，还对面孔凝视进行了分析，以评估发声行为的社会质量。结果显示，与TD组相比，ASD组在T2时的发音率较低，在T3时的第一词发音率较低。然而，在ASD组中，非社交喋喋不休的流行率似乎更高。这些发现对筛查项目的意义进行了讨论。
This study explores pre-linguistic vocal trajectories in infants with autism spectrum disorder (ASD) during caregiver-infant interaction. Home videos were obtained from 10 infants with ASD and 10 typically developing infants (TD), covering three time periods: 0-6 months (T1, 47 video sequences), 6-12 months (T2, 47 video sequences), and 12-18 months (T3, 48 video sequences). In total 142 video sequences were analyzed. Vocalizations, long reduplicated babbling, 2-syllable babbling, and first words were investigated longitudinally. Face-gazing was also analyzed, to evaluate the social quality of vocal behaviors. Results show a lower rate of vocalizations in the ASD group at T2, and a lower rate of first words at T3, compared to the TD group. However, the prevalence of non-social babbling, appeared higher in the ASD group. The implications of these findings for screening programs are discussed.