Immunodiagnosis of blastomycosis.

Immunodiagnosis of blastomycosis.
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芽生菌病的免疫诊断。

DOI:
10.1007/978-1-4615-3306-1_7
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发表时间:
1986
期刊:
Seminars in respiratory infections
影响因子:
--
通讯作者:
L. Kaufman
L. Kaufman
中科院分区:
--
文献类型:
--
作者:
S. Turner;L. Kaufman

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芽生真菌病的诊断长期以来一直是临床医生面临的一个挑战。芽生菌病主要是一种肺部疾病,仅凭临床症状很难与其他呼吸道感染区分开来。皮炎芽孢霉菌A抗原及其同源抗体的获得,以及这些试剂在诊断试验中的应用,大大提高了芽生真菌病的诊断水平。可靠的程序,准确和快速的免疫学诊断芽生真菌病是可用的。这些方法包括用于检测诊断血清抗体的酶免疫分析和免疫扩散试验,用于鉴定病原体菌丝状培养的外抗原试验,以及用于检测和鉴定培养物或组织中的酵母菌的荧光抗体技术。这些检测单独或联合使用,在许多情况下可以提供芽生菌病的早期和快速确诊。
The diagnosis of blastomycosis has long been a challenge for the clinician. Primarily a pulmonary disease, blastomycosis is difficult to differentiate from other respiratory infections by clinical symptoms alone. Substantial improvement in the diagnosis of blastomycosis can be attributed to the availability of the purified A antigen of Blastomyces dermatitidis and its homologous antibody and the incorporation of these reagents into diagnostic tests. Reliable procedures for accurately and rapidly immunodiagnosing blastomycosis are available. These methods comprise enzyme immunoassay and immunodiffusion tests for detecting diagnostic serum antibody by B dermatitidis, the exoantigen test for identifying mycelial-form cultures of the etiologic agent, and the fluorescent antibody technique for detecting and identifying yeast-form cells in culture or in tissue. These tests, used alone or in combination, can in many cases provide an early and rapid definitive diagnosis of blastomycosis.
皮炎芽生菌酵母相裂解物抗原的制备和 ELISA 评估。
DOI: 10.1016/0732-8893(88)90076-4
发表时间: 1988
影响因子: 2.9
作者:
Johnson,SM;Scalarone,GM
通讯作者: Scalarone,GM
芽生菌病胸膜疾病的谱系和意义。
DOI: 10.1378/chest.86.4.580
发表时间: 1984
期刊: Chest
影响因子: 9.6
作者:
Kinasewitz,GT;Penn,RL;George,RB
通讯作者: George,RB