Electrofusion of individual animal cells directly to intact corneal epithelial tissue.
Electrofusion of individual animal cells directly to intact corneal epithelial tissue.
复制标题
将单个动物细胞直接电融合到完整的角膜上皮组织。
DOI：
10.1016/0005-2736(89)90193-4
复制
发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Haller,EM
中科院分区：
文献类型：
--
作者：
Grasso,RJ;Heller,R;Cooley,JC;Haller,EM
本研究采用电融合技术将人和非人培养细胞直接电融合到兔角膜上皮组织上。利用这一新的过程成功地将功能性淋球菌膜附着受体从人淋巴瘤细胞到兔角膜上皮浅层。因此，细胞-组织电融合生物技术可用于建立独特的和新的动物模型，用于研究受体介导的过程在体内。
An electromechanical process was developed to electrofuse human and nonhuman cultured cells directly to rabbit corneal epithelial tissue in vitro and in situ. This new process was utilized successfully to incorporate functional gonococcal membrane attachment receptors from human lymphoma cells into superficial rabbit corneal epithelium. Thus, cell-tissue electrofusion biotechnology may be employed to establish unique and novel animal models for investigating receptor-mediated processes in vivo.