Neurocognition and conversion to psychosis in adolescents at high-risk.
Neurocognition and conversion to psychosis in adolescents at high-risk.
复制标题
高危青少年的神经认知和向精神病的转变。
DOI:
10.1016/j.schres.2007.12.477
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发表时间:
2008
影响因子:
4.5
通讯作者:
Walker,EF
中科院分区:
文献类型:
--
作者:
Walder,DJ;Mittal,V;Trotman,HD;McMillan,AL;Walker,EF
This study examined neurocognitive predictors of conversion to Axis I psychosis among adolescents at high-risk for psychosis (AHRP). There were no significant differences in neurocognitive performance between adolescents at high-risk for psychosis who converted (AHRP+) and adolescents at high-risk for psychosis who did not convert (AHRP−). Within-sex comparisons revealed a relation between risk status and performance among females, with AHRP+ performing below AHRP−, but this effect did not hold for males. Between-sex comparisons revealed AHRP− males performed worse than AHRP− females on several measures. Across groups, males performed better than their female counterparts on select measures. Results are discussed in terms of implications for use of neurocognitive profiles as bio-risk markers of psychosis, while considering sex differences.