Dynamic elongation of the vertebral artery during an in vitro whiplash simulation
Dynamic elongation of the vertebral artery during an in vitro whiplash simulation
复制标题
体外颈椎扭伤模拟过程中椎动脉的动态伸长
DOI：
10.1007/bf01322455
复制
发表时间：
2005
影响因子：
2.8
通讯作者：
J. Dvořák
中科院分区：
文献类型：
--
作者：
K. Nibu;J. Cholewicki;M. Panjabi;L. B. Babat;J. Grauer;R. Kothe;J. Dvořák
颈部扭伤的临床症状目前还不清楚。创伤期间椎动脉（VA）拉伸是一种可能的病理机制，可以解释挥鞭样综合征的某些方面。本研究使用体外模型量化了挥鞭样损伤模拟过程中的VA伸长。仔细解剖7例新鲜人尸体标本（枕骨至C7或TI），保留骨韧带结构。右侧VA更换为薄尼龙涂层柔性电缆。该电缆一端固定在枕骨上，另一端固定在专门设计的VA传感器上。用标准柔韧性测试测量枕骨的生理运动和VA的生理伸长。接下来，将试样安装在专门设计的滑板上，并经受2.5、4.5、6.5和8.5 g（1 g = 9.81 m/s2）的水平加速度。从创伤开始连续记录VA的延长。平均（标准差）生理VA延长在左侧弯时为5.8（1.6）mm，在左轴向旋转时为4.7（1.8）mm。屈曲和伸展并未导致VA出现任何明显的伸长。颈椎挥鞭样损伤时VA最大延长与滑车水平加速度显著相关（R2 = 0.7，P < 0.05）。在2.5、4.5、6.5和8.5 g创伤类别中，VA分别超出其生理范围1.0（2.1）、3.1（2.6）、8.9（1.6）和9.0（5.9）mm。
Clinical signs of whiplash are presently not well understood. Vertebral artery (VA) stretch during trauma is a possible pathomechanism that could explain some aspects of the whiplash symptom complex. This study quantified the VA elongation during whiplash simulation using an in vitro model. Seven fresh human cadaveric specimens (occiput to C7 or TI) were carefully dissected, preserving the osteoligamentous structures. The right VA was replaced with a thin nylon-coated flexible cable. This cable was fixed at one end to the occipital bone and at the other end to a specially designed VA transducer. Physiological motion of the occiput and physiological elongation of the VA were measured with a standard flexibility test. Next the specimen was mounted on a specially designed sled and subjected to 2.5, 4.5, 6.5, and 8.5 g (1 g = 9.81 m/s2) horizontal accelerations. Elongation of the VA was continuously recorded from the start of the trauma. The average (standard deviation) physiological VA elongation was 5.8 (1.6) mm in left lateral bending and 4.7 (1.8) mm in left axial rotation. Flexion and extension did not result in any appreciable elongation of the VA. The maximum VA elongation during the whiplash trauma significantly correlated with the horizontal acceleration of the sled (R2 = 0.7,P < 0.05). The VA exceeded its physiological range by 1.0 (2.1), 3.1 (2.6), 8.9 (1.6), and 9.0 (5.9) mm in the 2.5-, 4.5-, 6.5-, and 8.5-g trauma classes respectively.
DOI：
10.2106/00004623-199403000-00012
发表时间：
1994-03-01
影响因子：
5.3
作者：
PANJABI, MM;OXLAND, TR;CRISCO, JJ
通讯作者：
CRISCO, JJ