The use of soft robotics in cardiovascular therapy

The use of soft robotics in cardiovascular therapy
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DOI:
10.1080/14779072.2017.1366313
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发表时间:
2017-08
影响因子:
2
通讯作者:
I. Wamala;E. Roche;F. Pigula
I. Wamala;E. Roche;F. Pigula
中科院分区:
--
文献类型:
--
作者:
I. Wamala;E. Roche;F. Pigula

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摘要简介:机器人已被用于心血管治疗作为手术工具和医院系统的自动化。软机器人是一种由柔软的可变形材料制成的新型机器人,由于其固有的不太可能伤害身体组织并且更有可能适应生物环境,因此特别适合于生物医学应用。对正在开发的软机器人系统的认识将有助于促进临床医生参与其成功的临床翻译。涵盖的领域:最先进的软机器人系统,从纳米到宏观的尺寸范围,在心血管治疗的临床应用中表现出最大的希望,因为它们提供了仍然存在明确治疗需求的解决方案。我们讨论了纳米和微米级技术,可以帮助改善缺血性心脏病心脏再生的靶向治疗,以及用于机械循环支持的软机器人。此外,我们还指出了目前技术上的差距。专家评论:软机器人技术现在已经从概念验证阶段成熟到成功的动物试验。随着材料的进一步改进和临床医生的指导应用,它们将成为心血管治疗的有益补充。
ABSTRACT Introduction: Robots have been employed in cardiovascular therapy as surgical tools and for automation of hospital systems. Soft robots are a new kind of robot made of soft deformable materials, that are uniquely suited for biomedical applications because they are inherently less likely to injure body tissues and more likely to adapt to biological environments. Awareness of the soft robotic systems under development will help promote clinician involvement in their successful clinical translation. Areas covered: The most advanced soft robotic systems, across the size scale from nano to macro, that have shown the most promise for clinical application in cardiovascular therapy because they offer solutions where a clear therapeutic need still exists. We discuss nano and micro scale technology that could help improve targeted therapy for cardiac regeneration in ischemic heart disease, and soft robots for mechanical circulatory support. Additionally, we suggest where the gaps in the technology currently lie. Expert commentary: Soft robotic technology has now matured from the proof-of-concept phase to successful animal testing. With further refinement in materials and clinician guided application, they will be a useful complement for cardiovascular therapy.