Finite element analysis of the biomechanical interaction between coronary sinus and proximal anchoring stent in coronary sinus annuloplasty.
Finite element analysis of the biomechanical interaction between coronary sinus and proximal anchoring stent in coronary sinus annuloplasty.
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DOI：
10.1080/10255842.2012.758719
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发表时间：
2014
影响因子：
1.6
通讯作者：
Sun W
中科院分区：
文献类型：
--
作者：
Pham T;Deherrera M;Sun W
Recent clinical studies of the percutaneous transvenous mitral annuloplasty (PTMA) devices have shown a short-term reduction of mitral regurgitation (MR) after implantation. However, adverse events associated with the devices such as compression and perforation of vessel branches, device migration and fracture were reported. In this study, a finite element analysis was performed to investigate the biomechanical interaction between the proximal anchor stent of a PTMA device and the coronary sinus (CS) vessel in three steps including i) the stent release and contact with the CS wall, ii) the axial pull at the stent connector and iii) the pressure inflation of the vessel wall. To investigate the impact of the material properties of tissues and stents on the interactive responses, the CS vessel was modeled with human and porcine material properties, and the proximal stent was modeled with two different Nitinol materials with one being stiffer than the other. The results indicated that the vessel wall stresses and contact forces imposed by the stents were much higher in human than porcine models. However, the mechanical differences induced by the two stent types were relatively small. The softer stent exhibited a better fatigue safety factor when deployed in the human model than in the porcine model. These results underscored the importance of the CS tissue mechanical properties. Higher vessel wall stress and stent radial force were obtained in human model than those in porcine model, which also brought up questions as to the validity of using porcine model to assess device mechanical function. The quantification of these biomechanical interactions can offer scientific insight into the development and optimization of PTMA device design.
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影响因子：
37.8
作者：
Schofer J;Siminiak T;Haude M;Herrman JP;Vainer J;Wu JC;Levy WC;Mauri L;Feldman T;Kwong RY;Kaye DM;Duffy SJ;Tübler T;Degen H;Brandt MC;Van Bibber R;Goldberg S;Reuter DG;Hoppe UC
通讯作者：
Hoppe UC
影响因子：
2.3
作者：
Duffy, Stephen J.;Federman, Jacob;Kaye, David M.
通讯作者：
Kaye, David M.
影响因子：
9.7
作者：
Pham, Thuy;Sun, Wei
通讯作者：
Sun, Wei
影响因子：
6.1
作者：
El-Maasarany, S;Ferrett, CG;Henein, MY
通讯作者：
Henein, MY
影响因子：
2.3
作者：
Hoppe, Uta C.;Brandt, Mathias C.;Haude, Michael
通讯作者：
Haude, Michael