Directed self-assembly of polypeptide-engineered physical microgels for building porous cell-laden hydrogels.
Directed self-assembly of polypeptide-engineered physical microgels for building porous cell-laden hydrogels.
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DOI：
10.1039/c4cc04018j
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发表时间：
2014-07
影响因子：
4.9
通讯作者：
Ming-Hao Yao;Jie Yang;Ji-tao Song;Dong-hui Zhao;Mingchun Du;Yuanyang Zhao;Bo Liu
中科院分区：
文献类型：
--
作者：
Ming-Hao Yao;Jie Yang;Ji-tao Song;Dong-hui Zhao;Mingchun Du;Yuanyang Zhao;Bo Liu
提出了一种通过卷曲螺旋多肽在物理微凝胶表面自组装构建多孔载细胞水凝胶的新方法。通过调节微凝胶的多肽和形态特征，可以同时调节组装结构中的孔和物理微凝胶的细胞外微环境。
A novel approach to build porous cell-laden hydrogels through the self-assembly of coiled-coil polypeptides on the surface of physical microgels was developed. Both the extracellular microenvironments of pores and physical microgels within assembled constructs could be tailored simultaneously by tuning the polypeptide and morphological features of microgels.