Congenital diaphragmatic hernia: prenatal evaluation with MR lung volumetry--preliminary experience.
Congenital diaphragmatic hernia: prenatal evaluation with MR lung volumetry--preliminary experience.
复制标题
先天性膈疝：用 MR 肺容量进行产前评估——初步经验。
DOI：
10.1148/radiology.220.1.r01jl4163
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
Albanese,CT
中科院分区：
文献类型：
--
作者：
Paek,BW;Coakley,FV;Lu,Y;Filly,RA;Lopoo,JB;Qayyum,A;Harrison,MR;Albanese,CT
目的：为了确定观察者之间的变化产前磁共振（MR）肺容量和评估价值的MR肺容量的结果预测胎儿先天性肺herniates.MATERIALS和METHODS：产前MR成像进行了26例胎儿单侧先天性肺疝。两名独立观察员进行肺体积的平面测量。相对肺体积计算为观察到的总肺体积，表示为根据胎儿大小预测的总肺体积的百分比。相对肺体积与超声检查肺头比在左侧先天性腹股沟疝评估前27周妊娠（n= 21）和妊娠结局在所有情况下孤立的左侧先天性腹股沟疝没有产前干预（n= 11）。结果：观察者表现出良好的协议在MR成像的总肺体积测量，与组内相关系数为0.95。相对肺容积与肺头比呈正相关（r= 0.78，P <0.001）。通过对妊娠结局组进行秩次分析，校正分娩时的胎龄和出生体重后，相对肺体积是预后的预测因子（P<0.05）。四个胎儿的相对肺体积小于40%dead.CONCLUSION：观察者之间的协议是高MR肺容量测定，其结果是预测胎儿孤立性左侧先天性疝的结果。
PURPOSE:To determine the interobserver variability of prenatal magnetic resonance (MR) lung volumetry and to assess the value of MR lung volumetric findings as predictors of outcome in fetuses with congenital diaphragmatic hernia.MATERIALS AND METHODS:Prenatal MR imaging was performed in 26 fetuses with unilateral congenital diaphragmatic hernia. Two independent observers performed planimetric measurement of lung volume. Relative lung volume was calculated as the observed total lung volume expressed as a percentage of the total lung volume predicted from fetal size. Relative lung volume was correlated with the ultrasonographic lung-head ratio in left-sided congenital diaphragmatic hernias evaluated before 27 weeks gestation (n= 21) and with pregnancy outcome in all cases of isolated left-sided congenital diaphragmatic hernia without prenatal intervention (n= 11).RESULTS:Observers demonstrated excellent agreement in total lung volume measurements at MR imaging, with an intraclass correlation coefficient of 0.95. Relative lung volume was positively correlated with lung-head ratio (r= 0.78,P< .001). By using rank order analysis in the pregnancy outcome group, relative lung volume was predictive of prognosis (P< .05) when adjusted for gestational age at delivery and birth weight. Three of four fetuses with a relative lung volume of less than 40% died.CONCLUSION:Interobserver agreement is high at MR lung volumetry, and its findings are predictive of outcome in fetuses with isolated left-sided congenital diaphragmatic hernia.