m5C Goes Viral.
m5C Goes Viral.
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DOI:
10.1016/j.chom.2019.07.019
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发表时间:
2019-08
影响因子:
30.3
通讯作者:
Shelby Winans;K. Beemon
中科院分区:
文献类型:
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作者:
Shelby Winans;K. Beemon
In this issue ofCell Host & Microbe, Courtney et al. (2019a) find that HIV-1 genomic RNA has much more m5C than cellular mRNA. Deleting the m5C "writer" NSUN2 decreases HIV-1 m5C levels, promotes translation of the HIV-1 5′gaggene, and alters splicing at the A2 site.