EEG and ERP assessment of normal aging
EEG and ERP assessment of normal aging
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DOI：
10.1016/s0168-5597(97)96139-6
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发表时间：
1997-05-01
期刊：
影响因子：
--
通讯作者：
Polich, J
中科院分区：
文献类型：
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作者：
Polich, J
EEG记录了120名年龄从20岁到80岁以上的正常成人受试者在不同的眼睛打开/关闭条件下的EEG。在相同的被试者中，分别用听觉和视觉刺激诱发P3（00）事件相关脑电位（ERP）。频谱分析表明，总体EEG功率随受试者年龄的增加而降低。随着年龄的增长，听觉和视觉刺激条件下的P3振幅下降，峰值潜伏期增加。N1、P2或N2分量几乎没有观察到年龄相关的差异。δ，θ和α波段的频谱功率与受试者年龄范围内的P3振幅呈正相关，但平均波段频率与P3潜伏期仅表现出弱相关性。EEG和其他ERP成分变量之间没有很强的关系。结果表明，年龄有助于脑电功率的变化，这种变化显着影响与年龄相关的变化的P3 ERP组件。(C)1997 Elsevier Science爱尔兰有限公司
EEG was recorded from 120 normal adult subjects who ranged in age from 20 to 80 + years in separate eyes open/closed conditions. The P3(00) event-related brain potential (ERP) was elicited with auditory and visual stimuli in separate conditions in the same subjects. Spectral analysis indicated that overall EEG power decreased as subject age increased. P3 amplitude decreased and peak latency increased for both the auditory and visual stimulus conditions as subject age increased. Few age-related differences were observed for the N1, P2, or N2 components. Spectral power from the delta, theta, and alpha bands correlated positively with P3 amplitude across subject age, but mean band frequency demonstrated only weak associations with P3 latency. No strong relationships were found between EEG and the other ERP component variables. The results suggest that age contributes to EEG power shifts, and that such changes significantly affect age-related variability of the P3 ERP component. (C) 1997 Elsevier Science Ireland Ltd.