LYMPHATIC AND LOCAL SPREAD OF T1 AND T2 PANCREATIC-CANCER - A STUDY OF AUTOPSY MATERIAL
LYMPHATIC AND LOCAL SPREAD OF T1 AND T2 PANCREATIC-CANCER - A STUDY OF AUTOPSY MATERIAL
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DOI：
10.1097/00000658-198607000-00009
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发表时间：
1986-07-01
影响因子：
9
通讯作者：
MORIOKA, Y
中科院分区：
文献类型：
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作者：
NAGAI, H;KURODA, A;MORIOKA, Y
对 8 例具有 T1 和 T2 原发肿瘤的胰腺癌（导管细胞腺癌）尸检病例进行组织学研究，以检查淋巴和局部扩散的确切范围。其中六例在原发肿瘤附近的淋巴结中出现显微转移。此外，其中四例在主动脉旁区域有一些转移淋巴结。在淋巴转移的病例中，癌症在淋巴管、神经和/或结缔组织内的浸润程度几乎与淋巴结转移相同。 4 例发现主要血管受累。没有在胰腺中观察到癌细胞的多中心性或显着的导管内扩散的情况。有人认为，大多数 T1 和 T2 胰腺癌具有相当广泛的微观扩展，尽管极小的 T1 癌症具有非常有限的扩展。
Eight autopsy cases of pancreatic cancer (duct cell adenocarcinoma) with T1 and T2 primary tumors were studied histologically to examine the exact extent of lymphatic and local spread. Six of them had microscopic metastasis in grossly negative lymph nodes near the primary tumor. In addition, four of them had a few metastatic nodes in the para-aortic region. In cases with lymphatic metastases, the extent of cancer infiltration within lymphatic vessels, nerves and/or connective tissues was almost the same as that of lymph node metastasis. Major vascular involvement was found in four cases. There was no case in which multicentricity or marked intraductal spread of cancer cells was observed in the pancreas. It has been suggested that most of T1 and T2 pancreatic cancers have a fairly widespread microscopic extension, although extremely small T1 cancers have a very limited extension.