The intrauterine device: a bacteriologic study of the endometrial cavity.
The intrauterine device: a bacteriologic study of the endometrial cavity.
复制标题
宫内节育器：子宫内膜腔的细菌学研究。
DOI：
10.1016/s0002-9378(16)34650-6
复制
发表时间：
1966
影响因子：
9.8
通讯作者：
D. Moyer
中科院分区：
文献类型：
--
作者：
D. Mishell;James H. Bell;R. Good;D. Moyer
PIP：对两组不同的戴宫内节育器的患者采用两种方法获得的子宫内膜进行细菌学和组织学研究。第一组包括75例计划行选择性阴道子宫切除术联合阴道缝合术治疗症状性子宫和阴道松弛的患者。第二组由253名选择使用宫内节育器作为避孕手段的患者组成。第一组子宫切除术后经胃底培养，第二组经宫颈培养。当采用经宫底法时，无菌子宫内膜培养物的发生率明显更高。使用这种获得培养物的方法，发现从在前24小时内插入IUD的所有子宫中获得阳性子宫内膜培养物。放置后子宫内膜培养阳性的发生率迅速下降，因此放置IUD后1个月，所有检查的子宫内膜腔均无菌。研究结果证实了其他人的陈述，即使用尼龙线突出阴道的IUD的患者发生上生殖道临床感染通常是由于不相关的原因，如性交感染。甚至当线穿过污染的宫颈粘液时，从子宫内膜腔内的线部分以及环本身获得无菌培养物。
PIP: Bacterial and histologic studies were performed on endometrium obtained by 2 methods in 2 different groups of patients wearing the IUD. The first group consisted of 75 patients schedules to have elective vaginal hysterectomies in association with culporrhaphy for symptomatic uterine and vaginal relaxation. The second group was made up of 253 patients who elected to use the IUD as a contraceptive. Cultures were obtained transfundally after hysterectomy in the first group and transcervically in the second. The incidence of sterile endometrial cultures was significantly greater when the transfundal method was employed. Using this method of obtaining cultures, it was found that positive endometrial cultures were obtained from all uteri in which the IUD had been inserted within the previous 24-hour period. The incidence of positive endometrial cultures rapidly diminished at the time after insertion increased, so that after 1 month had elapsed since insertion of the IUD, all the endometrial cavities examined were sterile . The results of the study confirm the statements of others that the occurrence of clinical infection of the upper genital tract in patients having the IUD with nylon threads protruding into the vagina is usually due to an unrelated cause such as coital infection. Even when the threads passes through contaminated endocervical mucus, sterile cultures were obtained from the portion of the threads within the endometrial cavity as well as from the loop itself.