TETRODOTOXIN BLOCKS A GRADED SENSORY RESPONSE IN EYE OF LIMULUS

TETRODOTOXIN BLOCKS A GRADED SENSORY RESPONSE IN EYE OF LIMULUS
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DOI:
10.1126/science.155.3769.1576
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发表时间:
1967-01-01
期刊:
影响因子:
56.9
通讯作者:
RUSSELL, CJ
RUSSELL, CJ
中科院分区:
综合性期刊1区
文献类型:
--
作者:
BENOLKEN, RM;RUSSELL, CJ

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The generalization that tetrodotoxin selectively blocks all-or-none electrical activity of nerve and muscle but has negligible effect upon graded responses of sensory systems does not appear to be valid for the Limulus eye. Tetrodotoxin reversibly blocks the graded transient component of this visual response, while the steady state component of the response is relatively unaffected by the drug.