Bacteriocin diversity: ecological and evolutionary perspectives
Bacteriocin diversity: ecological and evolutionary perspectives
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DOI：
10.1016/s0300-9084(02)01421-9
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发表时间：
2002-05-01
期刊：
影响因子：
3.9
通讯作者：
Wertz, JE
中科院分区：
文献类型：
--
作者：
Riley, MA;Wertz, JE
细菌素家族是细菌防御系统中最丰富和最多样化的一组。细菌素的范围从被充分研究的由大肠杆菌产生的窄谱、高分子量大肠杆菌素和乳酸菌的短多肽羊毛硫抗生素到几乎普遍由好菌产生的相对未知的盐霉素。这一强大武器库的丰富性和多样性是显而易见的。不太清楚的是它们的进化起源以及它们在介导微生物相互作用中所起的作用。这篇综述的目的是探讨我们所知道的最具特征的细菌素家族，大肠杆菌素的进化和生态学。我们总结了目前的知识，这种非凡的蛋白质多样性是如何产生和维持在微生物种群中，这些毒素在介导微生物种群水平和社区水平的动态中发挥什么作用。(C)2002法国生物化学与生物分子学会/科学与医学版Elsevier SAS。All rights reserved.
The bacteriocin family is the most abundant and diverse group of bacterial defense systems. Bacteriocins range from the well-studied narrow spectrum, high molecular weight colicins produced by Escherichia coli and the short polypeptide lantibiotics of lactic acid bacteria to the relatively unknown halocins produced almost universally by the haolobacteria. The abundance and diversity of this potent arsenal of weapons is clear. Less clear is their evolutionary origins and the role they play in mediating microbial interactions. The goal of this review is to explore what we know about the evolution and ecology of the best-characterized family of bacteriocins, the colicins. We summarize current knowledge of how such extraordinary protein diversity arose and is maintained in microbial populations and what role these toxins play in mediating microbial population-level and community-level dynamics. (C) 2002 Societe francaise de biochimie et biologic moleculaire / Editions scientifiques et medicales Elsevier SAS. All rights reserved.