Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for generalized anxiety disorder and comorbid disorders: A randomized controlled trial

Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for generalized anxiety disorder and comorbid disorders: A randomized controlled trial
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DOI:
10.1016/j.janxdis.2015.09.003
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发表时间:
2015-12-01
影响因子:
10.3
通讯作者:
Titov, N.
Titov, N.
中科院分区:
医学2区
文献类型:
--
作者:
Dear, B. F.;Staples, L. G.;Titov, N.

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广泛性焦虑症(GAD)可以有效地治疗疾病特异性认知行为疗法(DS-CBT)或跨诊断CBT(TD-CBT)。DS-CBT和TD-CBT治疗GAD的相对获益以及以临床医生指导(CG-CBT)和自我指导(SG-CBT)形式提供治疗的相对获益尚未进行研究。GAD参与者(n=338)被随机分配接受以CG-CBT或SG-CBT格式提供的互联网提供的TD-CBT或DS-CBT干预。GAD症状的大幅减少(Cohen's d >= 1.48;平均减少>= 50%)和共病重度抑郁障碍(Cohen's d >= 1.64; avg.减少>= 45%)、社交焦虑障碍(Cohen's d >= 0.80; avg.减少>= 29%)和惊恐障碍(Cohen's d >= 0.55; avg.降低>= 33%)。DS-CBT和TD-CBT或CG-CBT和SG-CBT之间没有观察到实质性差异,突出了精心开发的TD-CBT和SG-CBT的公共卫生潜力。(C)2015年,作者。爱思唯尔有限公司出版
Generalized anxiety disorder (GAD) can be treated effectively with either disorder-specific cognitive behavior therapy (DS-CBT) or transdiagnostic CBT (TD-CBT). The relative benefits of DS-CBT and TD-CBT for GAD and the relative benefits of delivering treatment in clinician guided (CG-CBT) and self-guided (SG-CBT) formats have not been examined. Participants with GAD (n=338) were randomly allocated to receive an internet-delivered TD-CBT or DS-CBT intervention delivered in either CG-CBT or SG-CBT formats. Large reductions in symptoms of GAD (Cohen's d >= 1.48;avg. reduction >= 50%) and comorbid major depressive disorder (Cohen's d >= 1.64; avg. reduction >= 45%), social anxiety disorder (Cohen's d >= 0.80; avg. reduction >= 29%) and panic disorder (Cohen's d >= 0.55; avg. reduction >= 33%) were found across the conditions. No substantive differences were observed between DS-CBT and TD-CBT or CG-CBT and SG-CBT, highlighting the public health potential of carefully developed TD-CBT and SG-CBT. (C) 2015 The Authors. Published by Elsevier Ltd.