Prevalence and associated factors of knee osteoarthritis in a community-based population in Heilongjiang, Northeast China
Prevalence and associated factors of knee osteoarthritis in a community-based population in Heilongjiang, Northeast China
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DOI：
10.1007/s00296-010-1773-y
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发表时间：
2012-05-01
影响因子：
4
通讯作者：
Tao, Tianzun
中科院分区：
文献类型：
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作者：
Jiang, Liying;Rong, Jiesheng;Tao, Tianzun
关于中国东北地区膝关节OA的患病率及其相关因素的数据很少。本研究旨在评估社区居民中影像学和症状性膝关节骨性关节炎的患病率，并阐明相关的风险因素。采用非配对病例对照研究方法对膝关节骨性关节炎的危险因素进行研究。根据Kellgren和Lawrence分级方案对影像学OA进行评价。统计分析包括检验和逻辑回归模型。2005年东北地区社区健康调查共有1，196名40-84岁人群参加。调查参与者完成了一份基于采访者的问卷。症状性膝关节OA的标化患病率为16.05%，女性明显高于男性（19.87% vs.11.91%，= 13.76，P < 0.001）。随着年龄的增长，男性和女性均呈上升趋势（男性：x（2）= 29.67，P（趋势）< 0.001;女性：x（2）= 40.26，P（趋势）< 0.001）。症状性膝关节骨性关节炎患病率明显高于北京和汕头，低于内蒙古武川县，但差异无统计学意义。Logistic回归分析显示，年龄、性别、BMI和工作状况可能是城市居民膝关节OA的危险因素，而年龄、BMI和吸烟习惯可能是农村居民膝关节OA的危险因素。症状性膝关节骨性关节炎在老年妇女中极为常见，构成了一个主要的公共卫生问题。研究结果将有助于指导未来的卫生保健资源分配和预防策略。
Few data exist concerning the prevalence of knee OA and associated factors in Northeast China. This study was undertaken to estimate the prevalence of radiographic and symptomatic knee OA among community residents and to elucidate relevant risk factors. Unmatched case-control study was adopted to study risk factors of knee OA. Radiographic OA was evaluated according to the Kellgren and Lawrence grading scheme. Statistical analyses included tests and logistic model regressions. A total of 1,196 people aged 40-84 years participated in the community-based health survey in Northeast China in 2005. Survey participants completed an interviewer-based questionnaire. The standardized prevalence of symptomatic knee OA was 16.05% and it was significantly higher in women than in men (19.87% vs. 11.91%, = 13.76, P < 0.001). There was also an increased tendency with age in both sex (men: x (2) = 29.67, P (trend) < 0.001; women: x (2) = 40.26, P (trend) < 0.001). The prevalence of symptomatic knee OA was significantly higher than that in Beijing and Shantou, while lower than that in Wuchuan county of inner Mongolia with nonsignificant difference. Logistic regressions revealed that age, sex, BMI, and work status might be risk factors for knee OA in urban residents, whereas age, BMI, and smoking habits might be risk factors in rural dwellers. Symptomatic knee OA is extremely common with preponderance for elderly women and constitutes a major public health problem. The findings will be useful to guide the distribution of future health care resources and preventive strategies.