Ethnic and gender-specific incidence rates for hip fractures in South Africa: A multi-centre study
Ethnic and gender-specific incidence rates for hip fractures in South Africa: A multi-centre study
复制标题
DOI：
10.1016/j.bone.2020.115253
复制
发表时间：
2020-04-01
期刊：
影响因子：
4.1
通讯作者：
Cassim, B.
中科院分区：
文献类型：
--
作者：
Dela, S. S.;Paruk, F.;Cassim, B.
背景：关于南非(SA)髋部骨折发生率的数据有限。我们报告了SA髋部骨折的性别和种族发病率。方法：在SA三个省不同地理位置的直辖市进行的一项多中心前瞻性研究中，从2017年4月1日至2018年3月31日，对所有40岁及以上的受试者进行了结构化问卷调查，调查对象为新的非创伤性髋部骨折。根据统计数据计算髋部骨折的性别和种族发病率。结果：在2767名受试者中，1914名(69.2%)为女性，853名(30.8%)为男性。大多数受试者来自白人人口(40.9%)，其次是非洲人(26.4%)、有色人种(187%)和印度人(13.9%)。在整个群体中，男性髋部骨折患者明显比女性年轻(69岁[IQR 59-79]比77岁[IQR 68-84]，p<；0.001)。与其他种族群体相比，白人受试者年龄显著增大(P<；0.0001)，非洲人显著年轻(P<；0.0001)。在女性中，白种人的IR最高(176.0/100,000)，其次是印第安人(1,477/100,000)、有色人种(73.2/100,000)和非洲人(43.6/100,000)。在男性中也出现了类似的情况，尽管发病率较低，白人男性的IR最高，为每10万人中有76.5人。在整个研究人群和非洲人群中，60岁以下受试者中男性的IR高于女性。在白人人群中，男性的IR高于40-44岁年龄组的女性。而在有色人种和印第安人中，男性的IR分别在40-49岁和45-54岁年龄组中高于女性。在整个研究人群中，随着年龄的增长，女性和男性的相对风险比都有所增加。解释：南非所有种族都会发生髋部骨折，白人和印第安人的IR比有色人种和非洲人高。与已发表的文献一致的是，除年轻组外，女性髋部骨折的总体IR高于男性，且随年龄增长而增加。
Background: Limited data exist on the incidence of hip fractures in South Africa (SA). We report gender and ethnic specific incidence rates of hip fractures in SA.Methods: In a multicentre prospective study, conducted in geographically defined municipalities of three provinces in SA, a structured questionnaire was administered to all subjects aged 40 years and over, presenting with a new atraumatic hip fracture, from 1 April 2017 to 31 March 2018. Gender and ethnic specific incidence rates (IR) of hip fractures were calculated using population statistics from Statistics SA.Findings: Of the 2767 subjects enrolled, 1914 (69.2%) were women and 853 (30.8%) were men. The majority of subjects were from the White population (40.9%) followed by those from the African (26.4%), Coloured (187%) and Indian (13.9%) populations.Men with hip fractures were significantly younger than women in the total group (69 [IQR 59-79] versus 77 years [IQR 68-84], p < 0.001) and in each ethnic group. White subjects were significantly older (p < 0.0001) and Africans significantly younger (p < 0.0001) than the other ethnic groups.In women, the highest IR was noted in the White population (176.0 per 100,000), followed by that in the Indian (1477 per 100,000), Coloured (73.2 per 100,000) and African populations (43.6 per 100,000). A similar pattern was seen in men albeit at lower rates, with the highest rate in White men at 76.5 per 100,000.In the total study population and the African population, the IR was higher in men compared to women in subjects under 60 years. In the White population, the IR was higher in men compared to women in the 40-44 years age group. While in the Coloured and Indian populations the IR was higher in men compared to women in the 40-49 years and 45-54 years age groups, respectively.There was an increase in the relative risk ratios with age in the total study population, and in all ethnic groups in both women and men.Interpretation: Hip fractures occur in all ethnic groups in South Africa with higher IRs in the White and Indian populations compared to the Coloured and African populations. Consistent with the published literature, the overall hip fracture IR was higher in women than in men, except in the younger age groups, and increased with age.