The possible role of percutaneous tibial nerve stimulation using adhesive skin surface electrodes in patients with neurogenic detrusor overactivity secondary to spinal cord injury
The possible role of percutaneous tibial nerve stimulation using adhesive skin surface electrodes in patients with neurogenic detrusor overactivity secondary to spinal cord injury
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DOI：
10.1007/s11255-015-0911-6
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发表时间：
2015-03-01
影响因子：
2
通讯作者：
Li, Yao
中科院分区：
文献类型：
--
作者：
Chen, Guoqing;Liao, Limin;Li, Yao
比较使用皮肤表面粘附电极的经皮胫神经刺激（PTNS）与使用硫酸索利那新（SS）治疗脊髓损伤（SCI）继发性神经源性逼尿肌过度活动（NDO）患者的效果。对100例脊髓损伤继发NDO患者进行了随机对照研究。患者随机分为两组。A组患者使用皮肤表面粘附电极接受PTNS治疗4周。B组患者接受SS治疗4周。于治疗前及治疗后2、4周回顾膀胱日志及尿失禁生活质量问卷。治疗后2周和4周，两组患者膀胱日记各项指标较基线改善均有统计学意义（p < 0.05）， PTNS组与SS组间差异无统计学意义（p < 0.05）。与SS相比，PTNS与任何意想不到的不良事件无关。皮肤表面贴附电极PTNS治疗是治疗脊髓损伤继发性NDO的有效方法。该疗法不仅与SS疗法无差异，而且无创，易于患者管理。
To compare the effectiveness of percutaneous tibial nerve stimulation (PTNS) using adhesive skin surface electrodes versus solifenacin succinate (SS) in patients with neurogenic detrusor overactivity (NDO) secondary to spinal cord injury (SCI).A randomized controlled study involving 100 patients with NDO secondary to SCI was conducted. Patients were randomized into two groups. In group A, patients received PTNS using adhesive skin surface electrodes for 4 weeks. In group B, patients underwent SS treatment for 4 weeks. Bladder diaries and incontinence quality of life questionnaire were reviewed before treatment and 2 and 4 weeks after treatment.Improvement in all bladder diary parameters was statistically significant within each group 2 and 4 weeks after treatment compared to baseline (p < 0.05), but did not reach statistical significance between the PTNS and SS groups (p > 0.05). Compared to SS, PTNS was not associated with any unanticipated adverse events.PTNS therapy with adhesive skin surface electrodes is an effective method to treat NDO secondary to SCI. This therapy is not only no difference comparing to SS therapy but also noninvasive and easily managed by patients.