Freezing of gait in Parkinson's disease: a perceptual cause for a motor impairment?
Freezing of gait in Parkinson's disease: a perceptual cause for a motor impairment?
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DOI：
10.1136/jnnp.2008.160580
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发表时间：
2010-05-01
影响因子：
11
通讯作者：
Lebold, C. A.
中科院分区：
文献类型：
--
作者：
Almeida, Q. J.;Lebold, C. A.
虽然冻结步态 (FOG) 通常被认为是一种运动障碍，但事实上，它更频繁地发生在密闭空间中，这表明对空间的感知可能会导致 FOG。本研究评估了门口尺寸如何影响可能表明冻结的步态特征。在三个不同组中走过三个不同尺寸的门口（窄（0.675 m 宽 x 2.1 m 高）、正常（0.9 m 宽 x 2.1 m 高）和宽（1.8 m 宽 x 2.1 m 高））时，评估了步态时空方面的变化：15 名帕金森病患者在测试时确认患有 FOG； 16 名患有帕金森病的非 FOG 个体和 16 名年龄匹配的健康对照参与者。步长结果表明，FOG 组受狭窄门口的影响最大，并且是唯一一个步长取决于即将到来的门口尺寸的组，如各组条件之间的显着交互作用所示 (F(4,88)=2.73，p
While freezing of gait (FOG) is typically considered a motor impairment, the fact that it occurs more frequently in confined spaces suggests that perception of space might contribute to FOG. The present study evaluated how doorway size influenced characteristics of gait that might be indicative of freezing. Changes in spatiotemporal aspects of gait were evaluated while walking through three different-sized doorways (narrow (0.675 m wide x 2.1 m high), normal (0.9 m wide x 2.1 m high) and wide (1.8 m wide x 2.1 m high)) in three separate groups: 15 individuals with Parkinson's disease confirmed to be experiencing FOG at the time of test; 16 non-FOG individuals with Parkinson's disease and 16 healthy age-matched control participants. Results for step length indicated that the FOG group was most affected by the narrow doorway and was the only group whose step length was dependent on upcoming doorway size as indicated by a significant interaction of group by condition (F(4,88)=2.73, p