Effects of a smartphone app-based diet and physical activity program for men living with HIV who have dyslipidemia: A pilot randomized controlled trial
Effects of a smartphone app-based diet and physical activity program for men living with HIV who have dyslipidemia: A pilot randomized controlled trial
复制标题
DOI：
10.1111/jjns.12535
复制
发表时间：
2023-04-15
影响因子：
1.7
通讯作者：
Maeda, Hitomi
中科院分区：
文献类型：
--
作者：
Aomori, Maki;Matsumoto, Chiharu;Maeda, Hitomi
目的：由于抗逆转录病毒疗法的使用和慢性炎症，艾滋病毒感染者患心血管疾病的风险很高。通过改变生活方式来评估血脂水平的证据有限。本研究旨在评估基于智能手机应用程序的饮食和运动改善计划对患有艾滋病毒和血脂异常的男性的影响。方法：这是一项随机对照试验，招募患有血脂异常的日本艾滋病毒感染者：干预组（n = 19）和对照组（n = 19）。干预组在为期 6 个月的干预期间接受了第三次个人指导，并鼓励他们在智能手机应用程序上记录他们的饮食。对结果进行了意向治疗分析。 结果：与对照组相比，从基线到干预后 6 个月，干预组的低密度脂蛋白水平变化显着降低（-4.00 +/- 20.2 mg/dL vs. 10.11 +/- 21.1 mg/dL）(p = .042)。其他血脂水平未发现显着差异。从基线到干预后 6 个月，干预组的腹围显着下降 (p = .048)。从基线到干预后 6 个月，干预组的总能量、蛋白质、碳水化合物、脂肪和盐摄入量、饮食和身体活动行为变化阶段和社会支持、饮食自我效能和孤独感显着改善 (p < .05)。结论：基于日本特定健康指南的智能手机应用程序的饮食和身体活动改善计划可能会降低该人群中的低密度脂蛋白胆固醇水平。需要进一步扩大样本并检查长期影响。
Aims: People living with HIV are at a high risk for cardiovascular disease owing to antiretroviral therapy use and chronic inflammation. There is limited evidence on the evaluation of serum lipid levels through lifestyle modification. This study aims to evaluate the effect of a smartphone application-based diet and exercise improvement program on men living with HIV and dyslipidemia.Methods: This was a randomized controlled trial recruiting Japanese men living with HIV who have dyslipidemia: intervention group (n = 19) and control group (n = 19). The intervention group received a third individual guidance session during the 6-month intervention and was encouraged to record their diet on a smartphone application. An intention-to-treat analysis of the results was conducted.Results: The intervention group showed significantly reduced change in low-density lipoprotein levels compared to the control group (-4.00 +/- 20.2 mg/dL vs. 10.11 +/- 21.1 mg/dL) (p = .042) from baseline to 6 months post-intervention. No significant differences were found in other serum lipid levels. Abdominal circumference decreased significantly in the intervention group (p = .048) from baseline to 6 months post-intervention. Total energy, protein, carbohydrate, fat, and salt intake, dietary and physical activity behavior change stages and social support, dietary self-efficacy, and loneliness significantly improved in the intervention group (p < .05) from baseline to 6 months post-intervention.Conclusions: A diet and physical activity improvement program using a smartphone application based on Japanese-specific health guidance may reduce low-density lipoprotein cholesterol levels in this population. Further sample expansion and examination of long-term effects are needed.