Improved Aortic Pulse Wave Velocity Assessment From Multislice Two-Directional In-Plane Velocity-Encoded Magnetic Resonance Imaging
Improved Aortic Pulse Wave Velocity Assessment From Multislice Two-Directional In-Plane Velocity-Encoded Magnetic Resonance Imaging
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DOI：
10.1002/jmri.22359
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发表时间：
2010-11-01
影响因子：
4.4
通讯作者：
Reiber, Johan H. C.
中科院分区：
文献类型：
--
作者：
Westenberg, Jos J. M.;de Roos, Albert;Reiber, Johan H. C.
目的：目的：评价平面内速度编码磁共振成像（in-plane velocity-encoded magnetic resonance imaging，MRI）测量主动脉脉搏波速度（pulse wave velocity，PWV）的准确性和重复性。并与常规评估的多部位单向通过平面速度编码MRI（PWVt.p.）的PWV进行比较。在患者中，PWV也是从动脉内获得的压力-时间曲线（PWVpressure）获得的，这被认为是金标准参考方法。结果：在患者中，PWVi.p.与PWVt. p.相比，PWVi.p.与PWVpressure的相关性更强，且变化趋势相似。（Pearson相关系数r = 0.75 vs. r = 0.58，变异系数[COV] = 10% vs. COV = 12%）。在志愿者中，重复PWVi.p.评估显示出比重复PWVt.p.更强的相关性和更小的变异性。（近端主动脉：r = 0.97和COV = 10% vs. r = 0.69和COV = 17%;远端主动脉：r = 0.94和COV = 12% vs. r = 0.90和COV = 16%;总主动脉：结论：PWVi.p.与常规PWVt.p.相比，具有更高的一致性（与金标准（PWVpressure）相比）和更高的重复性（用于MRI评估）。
Purpose: To evaluate the accuracy and reproducibility of aortic pulse wave velocity (PWV) assessment by in-plane velocity-encoded magnetic resonance imaging (MRI).Materials and Methods: In 14 patients selected for cardiac catheterization on suspicion of coronary artery disease and 15 healthy volunteers, PWV was assessed with multislice two-directional in-plane velocity-encoded MRI (PWVi.p.) and compared with conventionally assessed PWV from multisite one-directional through-plane velocity-encoded MRI (PWVt.p.). In patients, PWV was also obtained from intraarterially acquired pressure-time curves (PWVpressure), which is considered the gold standard reference method. In volunteers, PWVi.p. and PWVt.p. were obtained in duplicate in the same examination to test reproducibility.Results: In patients, PWVi.p. showed stronger correlation and similar variation with PWVpressure than PWVt.p.). (Pearson correlation r = 0.75 vs. r = 0.58, and coefficient of variation [COV] = 10% vs. COV = 12%, respectively). In volunteers, repeated PWVi.p. assessment showed stronger correlation and less variation than repeated PWVt.p. (proximal aorta: r = 0.97 and COV = 10% vs. r = 0.69 and COV = 17%; distal aorta: r = 0.94 and COV = 12% vs. r = 0.90 and COV = 16%; total aorta: r = 0.97 and COV = 7% vs. r = 0.90 and COV = 13%).Conclusion: PWVi.p. is an improvement over conventional PWVt.p. by showing higher agreement as compared to the gold standard (PWVpressure) and higher reproducibility for repeated MRI assessment.