Intradermal blue dye to identify sentinel lymphnode in breast cancer
Intradermal blue dye to identify sentinel lymphnode in breast cancer
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DOI：
10.1016/s0140-6736(05)62634-7
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发表时间：
1997-06-07
期刊：
影响因子：
168.9
通讯作者：
Pijpers, R
中科院分区：
文献类型：
--
作者：
Borgstein, PJ;Meijer, S;Pijpers, R
SIR—Colleagues and I have long been interested in the role of sentinel lymphadenectomy in patients with primary breast cancer, 1–4 and I am intrigued by the report of Paul Borgstein and colleagues (June 7, p 1668). 5 Their technique is conceptually valid and could be of practical value. I am concerned, however, about the longterm cosmetic effect of blue dye injected in the skin of the breast. Breast oedema is quite common after breast-conserving therapy (partial mastectomy, axillarynode dissection, and postoperative radiation) and may retard dissipation of the dye from the injection site. I have found that occasionally even subcutaneous injection of isosulfan blue dye may leave a slight blue haze that does not disappear quickly and, indeed, may last as long a year. Although this has not been troublesome, I suspect that injecting the skin could leave an obvious blue mark. Critics of dye-based lymphatic mapping have expressed concern about possible tattooing. Have Borgstein and co-workers observed a blue tattoo after injection of intradermal dye, and could it affect the clinical utility of their observation?
