Correlation of kinetic energy losses in high-energy collision-induced dissociation with observed peptide product ions.
Correlation of kinetic energy losses in high-energy collision-induced dissociation with observed peptide product ions.
复制标题
高能碰撞诱导解离中动能损失与观察到的肽产物离子的相关性。
DOI：
10.1021/ac950893r
复制
发表时间：
1996
影响因子：
7.4
通讯作者：
Glish,GL
中科院分区：
文献类型：
--
作者：
Vachet,RW;Winders,AD;Glish,GL
在碰撞诱导解离中，入射母离子的动能中的一些在与中性靶碰撞时被转换成内能。损失的动能与沉积到任何单个离子中的内能的量有关。要在相同的时间尺度上看到不同临界能量的离解，需要沉积不同数量的内能。这应该反映在母离子在形成不同产物离子时损失的动能中。这里报告了不同肽产物离子形成中的能量损失的变量。可以看出，不同的产物离子类型（B，y，a）显示出能量损失的有序模式。对于b型产物离子的形成观察到比y型更大的能量损失，并且对于a型产物离子的形成观察到甚至更大的能量损失。离子类型的能量损失和离子质量之间的一个很好的相关性进行了观察。因此，测量产物离子形成中的能量损失可提供用于对产物离子类型进行分类的手段。
In collision-induced dissociation, some of an incident parent ion's kinetic energy is converted into internal energy upon collision with a neutral target. The kinetic energy lost is related to the amount of internal energy deposited into any individual ion. To see dissociations of different critical energies on the same time scale, different amounts of internal energy need to be deposited. This should be reflected in the kinetic energy lost by the parent ion in the formation of different product ions. Variable amounts of energy loss in the formation of different peptide product ions are reported here. It is seen that different product ion types (b, y, a) show ordered patterns of energy losses. A greater energy loss is observed for the formation of b-type product ions than for y-type, and even greater energy losses are observed for the formation of a-type product ions. A very good correlation between ion type energy loss and ion mass is observed. Thus, measuring the energy losses in the formation of product ions may provide a means for classifying the product ion type.