Stroke and migraine: a cardiologist's headache
Stroke and migraine: a cardiologist's headache
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DOI：
10.1136/hrt.2008.154963
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发表时间：
2009-04-01
期刊：
影响因子：
5.7
通讯作者：
Meier, Bernhard
中科院分区：
文献类型：
--
作者：
Meier, Bernhard
“中风和偏头痛：心脏病专家的头痛”这个令人费解的标题让人联想到一个潜在的共同原因：通过卵圆孔未闭（PFO）的心脏右向左分流。16世纪，意大利外科医生Botallo首次描述了PFO， 1877年，德国病理学家Cohnheim发表了PFO介导中风的怀疑。此后，通过尸检研究（20-35%），经胸超声心动图（7-24%），或更敏感的经食管超声心动图（20-40%）确定了成人PFO的患病率。第一篇将PFO与卒中联系起来的主要临床论文出现在1983年，1992年首次报道了经皮缝合术。8
The puzzling title ‘‘stroke and migraine: a cardiologists’ headache’’conjures up a potential common cause: a cardiac right-to-left shunt through a patent foramen ovale (PFO). In the 16th century the Italian surgeon Botallo first described the PFO and in 1877 the suspicion of a PFO mediated stroke was published by the German pathologist Cohnheim. Since then the prevalence of PFO in adults has been established by autopsy studies (20–35%), 1 2 transthoracic echocardiography (7–24%), 3 4 or by the more sensitive transoesophageal echocardiography (20–40%). 5–7 The first major clinical paper associating PFO and stroke appeared in 19883 and the first reporting percutaneous closure in 1992. 8