Thymic large cell neuroendocrine carcinoma: report of a resected case - a case report
Thymic large cell neuroendocrine carcinoma: report of a resected case - a case report
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DOI：
10.1186/1749-8090-5-115
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发表时间：
2010-11-22
影响因子：
1.6
通讯作者：
Satoh, Yukitoshi
中科院分区：
文献类型：
--
作者：
Ogawa, Fumihiro;Iyoda, Akira;Satoh, Yukitoshi
胸腺大细胞神经内分泌癌（LCNECs）非常罕见。我们在这里描述的情况下，肿瘤可以完全切除。一位55岁男性因定期健康检查发现的前纵隔肿瘤而入院治疗。病人接受了扩大胸腺切除术的侵袭性胸腺瘤的Masaoka的第二阶段，已被怀疑术前。肿瘤位于胸腺右叶，并被完全切除。手术标本的最终病理诊断为胸腺LCNEC。根据肺LCNEC的诊断，患者接受了伊立替康和顺铂辅助化疗，术后16个月存活，无复发或转移。
Thymic large cell neuroendocrine carcinomas (LCNECs) are very rare. We here describe a case in which the tumor could be completely resected. A 55-year-old male was admitted to our hospital for treatment of an anterior mediastinal tumor found at a regular health check-up. The patient underwent an extended thymectomy of an invasive thymoma of Masaoka's stage II that had been suspected preoperatively. The tumor was located in the right lobe of the thymus and was completely resected. Final pathological diagnosis of the surgical specimen was thymic LCNEC. The patient underwent adjuvant chemotherapy with irinotecan and cisplatin in accordance with the diagnosis of a lung LCNEC, and is alive without recurrence or metastasis 16 months after surgery.