Serotype, biotype, pyrogenic exotoxin, streptolysin O and exoenzyme patterns of invasive Streptococcus pyogenes isolates from patients with toxin shock syndrome, bacteremia and other severe infections.
Serotype, biotype, pyrogenic exotoxin, streptolysin O and exoenzyme patterns of invasive Streptococcus pyogenes isolates from patients with toxin shock syndrome, bacteremia and other severe infections.
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毒素休克综合征、菌血症和其他严重感染患者分离的侵袭性化脓性链球菌的血清型、生物型、热原性外毒素、链球菌溶血素 O 和外酶模式。
DOI：
10.1007/978-1-4899-1825-3_58
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发表时间：
1997
影响因子：
--
通讯作者：
J. Alouf
中科院分区：
文献类型：
--
作者：
H. Müller;C. Geoffroy;P. Geslin;A. Bouvet;A. Felten;E. Günther;J. Ozegowski;W. Reichardt;J. Alouf
最近，包括链球菌中毒性休克综合征 (STSS) 在内的严重侵袭性 A 族链球菌 (GAS) 感染的增加似乎与细菌和宿主因素的组合有关 1, 2, 3, 4。据信与之相关的细菌效应物是 M 蛋白的某些血清型以及各种细胞外毒素和酶，例如链球菌热原性（红原性）外毒素 A 和 C（SPE A、SPE） C)、链球菌溶血素 O (SLO) 和半胱氨酸蛋白酶（已证明与 SPE B 相同）。还测定了培养物上清液中链激酶 (SK) 和透明质酸酶 (HA) 的滴定。
The recent increase of severe invasive group A streptococcal (GAS) infections including streptococcal toxic shock syndrome (STSS) appears to be related to a combination of both bacterial and host factors1, 2, 3, 4. The bacterial effectors which are believed to be causally involved are certain serotypes of M protein and various extracellular toxins and enzymes such as streptococcal pyrogenic (erythrogenic) exotoxins A and C (SPE A, SPE C), streptolysin O (SLO), and cysteine proteinase which has been shown to be identical to SPE B. The titration of streptokinase (SK) and hyaluronidase (HA) in culture supernatants was also determined.