Prevalence of Neuropsychiatric Symptoms in Chinese Older Persons With Mild Cognitive Impairment-A Population-Based Study
Prevalence of Neuropsychiatric Symptoms in Chinese Older Persons With Mild Cognitive Impairment-A Population-Based Study
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DOI：
10.1097/jgp.0b013e3181d69467
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发表时间：
2010-10-01
影响因子：
7.2
通讯作者：
Chiu, Helen Fung-Kum
中科院分区：
文献类型：
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作者：
Chan, Wai-Chi;Lam, Linda Chiu-Wa;Chiu, Helen Fung-Kum
目的：评估中国社区轻度认知功能障碍（MCI）和认知功能正常（NC）老年人神经精神（NP）症状的时点患病率及其相关性。设计：横断面研究来自MCI和痴呆的人群患病率研究。地点及参与者：本调查于2005至2006年在香港进行。招募了788名社区老年人（450名NC和338名MCI）。获得认知和NP数据。结果如下：NC和MCI中至少一种NP症状的点患病率分别为29%和36.7%（年龄和教育控制的逻辑回归，比值比= 1.38，95%置信区间[CI]：1.01-1.89，Wald chi（2）= 4.10，df = 1，p = 0.04）。在MCI受试者中，躁动（1.8%对5.1%）、冷漠（7.6%对15.2%）和易怒（4.2%对8%）更为普遍（p
Objectives: To estimate the point prevalence and correlates of neuropsychiatric (NP) symptoms among older adults with mild cognitive impairment (MCI) and normal cognition (NC) in a Chinese community. Design: Cross-sectional study derived from a population-based prevalence study of MCI and dementia. Setting and Participants: This survey was conducted in Hong Kong from 2005 to 2006. Seven hundred eighty-eight community-dwelling older adults (450 NC and 338 MCI) were recruited. Cognitive and NP data were obtained. Results: The point prevalence of at least one NP symptom in NC and MCI were 29% and 36.7%, respectively (logistic regression controlled for age and education, odds ratio = 1.38, 95% confidence interval [CI]: 1.01-1.89, Wald chi(2) = 4.10, df = 1, p = 0.04). Agitation (1.8% versus 5.1%), apathy (7.6% versus 15.2%), and irritability (4.2% versus 8%) were more prevalent in subjects with MCI (p