Laser Ablation for Cancer: Past, Present and Future.
Laser Ablation for Cancer: Past, Present and Future.
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DOI：
10.3390/jfb8020019
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发表时间：
2017-06-14
影响因子：
4.8
通讯作者：
Fong Y
中科院分区：
文献类型：
--
作者：
Schena E;Saccomandi P;Fong Y
激光消融（LA）作为手术切除的替代方案，越来越被接受作为肿瘤治疗的方法。本文回顾了激光在消融和外科手术中的应用。还审查了旨在改善 LA 结果的解决方案：LA 期间的高温治疗计划工具和测温技术，用于指导外科医生选择和调整最佳激光设置，以及纳米颗粒的潜在使用，以实现消融治疗的生物选择性。有前景的技术解决方案和对激光与组织相互作用的更好了解将使 LA 能够以安全有效的方式用于癌症治疗。
Laser ablation (LA) is gaining acceptance for the treatment of tumors as an alternative to surgical resection. This paper reviews the use of lasers for ablative and surgical applications. Also reviewed are solutions aimed at improving LA outcomes: hyperthermal treatment planning tools and thermometric techniques during LA, used to guide the surgeon in the choice and adjustment of the optimal laser settings, and the potential use of nanoparticles to allow biologic selectivity of ablative treatments. Promising technical solutions and a better knowledge of laser-tissue interaction should allow LA to be used in a safe and effective manner as a cancer treatment.