Descriptive epidemiology of infantile cataracts in metropolitan Atlanta, Ga, 1968-1998
Descriptive epidemiology of infantile cataracts in metropolitan Atlanta, Ga, 1968-1998
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DOI：
10.1001/archpedi.157.4.341
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发表时间：
2003-04-01
影响因子：
--
通讯作者：
Rasmussen, SA
中科院分区：
文献类型：
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作者：
Bhatti, TR;Dott, M;Rasmussen, SA
背景：婴幼儿白内障是儿童视力障碍的重要原因。为获得最佳的视觉效果，建议在6周前进行手术。目的：识别高危人群，促进婴幼儿白内障患者的成功治疗。方法：1968-1998年间，采用亚特兰大先天缺陷监测项目，采用积极的病例确定方法，对出生一年内确诊的婴幼儿白内障进行鉴定。分析了出生年份、性别、种族、母亲年龄、多胎(单胎与多胎)、胎龄、出生体重、偏侧性、季节性和确诊年龄等因素。结果：共确诊199例婴儿白内障，发病率为2.03/万。在117名婴儿(59%)中，白内障是孤立的缺陷；在43名婴儿(220/0)中，白内障是综合征的一部分；在39名婴儿(20%)中，还存在额外的、无关的重大出生缺陷。低出生体重儿(体重较重的婴儿)的比率较高
Background: Infantile cataract is an important cause of childhood visual impairment. Surgery before 6 weeks of age is recommended for optimal visual outcome. Description of the epidemiologic characteristics of cataracts is important for an improved understanding of the condition.Objectives: To identify at-risk populations and facilitate successful treatment of patients with infantile cataracts.Methods: Infants with cataracts diagnosed in the first year of life were identified using the Metropolitan Atlanta Congenital Defects Program, a birth defects surveillance program with active methods of case ascertainment, for the years 1968-1998. Several factors Were analyzed, including year of birth, sex, race, maternal age, plurality (single vs multiple gestation), gestational age, birth weight, laterality, seasonality, and age at diagnosis.Results: A total of 199 infants with cataracts were identified, for a rate of 2.03 per 10 000 births. In 117 infants (59%), cataracts occurred as an isolated defect; in 43 infants (220/0), cataracts occurred as part of a syndrome; and in 39 infants (20%), additional, unrelated, major birth defects were also present. Rates were higher for low-birth-weight infants (those weighing