Electronic Nicotine Delivery Systems (ENDS) Use and Pregnancy II: Perinatal Outcomes Following ENDS Use During Pregnancy.

Electronic Nicotine Delivery Systems (ENDS) Use and Pregnancy II: Perinatal Outcomes Following ENDS Use During Pregnancy.
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DOI:
10.1007/s40429-021-00381-9
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发表时间:
2021-09
影响因子:
4.3
通讯作者:
Weinberger AH
Weinberger AH
中科院分区:
医学3区
文献类型:
--
作者:
DeVito EE;Fagle T;Allen AM;Pang RD;Petersen N;Smith PH;Weinberger AH

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这篇综述考察了妊娠期使用电子尼古丁递送系统(END)后不良围产期结局的风险,并考虑是否有足够的数据支持END作为妊娠期减少伤害的方法。七篇论文评估了怀孕期间使用终端后的围产儿结局。有证据表明,终端使用与某些不良围产期结局(例如,小于胎龄)的风险增加有关。然而,重复使用数据集、数据不足(例如,使用终端的时间、使用的终端产品的类型)以及有限的样本量,导致了关于终端使用(单独或与可燃香烟(CC)结合使用)与单独使用CC相比对不良围产期后果的风险的程度的混合结论。目前的数据仍然不足以支持Ends作为一种减少伤害的方法,尽管研究结果确实值得关注,并对Ends在怀孕期间的使用进行了更详细的调查。未来的研究方向,以及对临床建议和烟草管理科学的影响进行了讨论。
This review examines the risk of adverse perinatal outcomes following electronic nicotine delivery system (ENDS) use during pregnancy, and considers whether there are sufficient data to support ENDS as a harm reduction approach during pregnancy. Seven papers assessed perinatal outcomes following ENDS use during pregnancy. There was evidence that ENDS use was associated with increased risk for some adverse perinatal outcomes (e.g., small for gestational age). However, the repeated use of data sets, insufficient data (e.g., timing of ENDS use, type of ENDS products used), and limited samples size, contributed to mixed findings on the degree to which ENDS use (alone or in combination with combustible cigarettes (CC)) impacts the risk of adverse perinatal outcomes relative to CC smoking alone. The current data are still insufficient to support ENDS as a harm reduction approach, though findings do warrant concern and more detailed investigation of ENDS use during pregnancy. Future research directions, as well as implications for clinical recommendations and tobacco regulatory science are discussed.
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