Modus operandi of the bacterial RNA polymerase containing the σ54 promoter-specificity factor
Modus operandi of the bacterial RNA polymerase containing the σ54 promoter-specificity factor
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DOI：
10.1111/j.1365-2958.2008.06181.x
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发表时间：
2008-05-01
影响因子：
3.6
通讯作者：
Buck, Martin
中科院分区：
文献类型：
--
作者：
Wigneshweraraj, Sivaramesh;Bose, Daniel;Buck, Martin
细菌sigma（sigma）因子赋予RNA聚合酶基因特异性，RNA聚合酶是催化基因转录的中心酶。选择性sigma因子sigma（54）的结合赋予RNA聚合酶特殊的功能和调节特性，使其适合于控制几种主要的适应性反应。在这里，我们总结了我们目前对sigma（54）因子与细菌转录机制相互作用的理解。
Bacterial sigma (sigma) factors confer gene specificity upon the RNA polymerase, the central enzyme that catalyses gene transcription. The binding of the alternative sigma factor sigma(54) confers upon the RNA polymerase special functional and regulatory properties, making it suited for control of several major adaptive responses. Here, we summarize our current understanding of the interactions the sigma(54) factor makes with the bacterial transcription machinery.