Deep inside Multifocal Choroiditis: an Optical Coherence Tomography Angiography approach
Deep inside Multifocal Choroiditis: an Optical Coherence Tomography Angiography approach
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DOI：
10.1007/s10792-016-0300-x
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发表时间：
2017-08-01
影响因子：
1.6
通讯作者：
Cagini, Carlo
中科院分区：
文献类型：
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作者：
Cerquaglia, Alessio;Lupidi, Marco;Cagini, Carlo
本研究的目的是报告光学相干断层血管成像(OCT-A)在多灶性脉络膜炎(MFC)炎性病变和脉络膜新生血管(CNV)鉴别诊断中的临床应用价值。对1例主诉中心视力丧失和左眼暗点的MFC患者进行了基于染料的血管造影、结构OCT和OCT-A的全面检查。黄斑CNV的重新激活最初被怀疑，而OCT-A显示视网膜色素上皮(RPE)以及RPE和Bruchs膜之间没有任何去相关信号。OCT-A是检测炎性CNV和鉴别CNV与原发炎性损伤的一种有前景的工具。精细地描述病变的特征使我们能够选择最佳的治疗策略来管理这些潜在的致盲疾病。
The aim of the study was to report the clinical utility of optical coherence tomography angiography (OCT-A) in characterizing and differentiating inflammatory lesions and choroidal neovascularization (CNV) in multifocal choroiditis (MFC). A patient affected by MFC complaining central visual loss and scotoma in his left eye was fully investigated with dye-based angiographies, structural OCT and OCT-A. A reactivation of macular CNV was initially suspected, while OCT-A revealed the absence of any decorrelation signal both over the retinal pigment epithelium (RPE) and between RPE and Bruchs' membrane. OCT-A is a promising tool in detecting inflammatory CNV and in differentiating CNV from primitive inflammatory damage. Finely characterizing the aspect of a lesion allows us to choose the best therapeutic strategy for managing these potentially blinding diseases.