OXYGEN SHUNTING IN RENAL CORTICAL AND MEDULLARY CAPILLARIES

OXYGEN SHUNTING IN RENAL CORTICAL AND MEDULLARY CAPILLARIES
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DOI:
10.1152/ajplegacy.1961.200.1.159
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发表时间:
1961-01-01
影响因子:
--
通讯作者:
IMPERIAL, ES
IMPERIAL, ES
中科院分区:
其他
文献类型:
--
作者:
LEVY, MN;IMPERIAL, ES

文献摘要

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在将高氧分压和含有光学标记的红细胞的血液注射到肾动脉中后,从肾静脉血的密度计描记确定存在从肾毛细血管床的动脉到静脉段的氧分流。肾皮质的外部区域通过区域低温从髓质加内部皮质功能上分离。通过冷却肾脏的浅表或深部区域,未观察到氧气分流的肾密度计示踪特征的双相特征的一致性放大或衰减。可以得出结论,分流的氧气发生在肾皮质和髓质,但它发生在每个区域的程度不能从目前的数据进行量化。
The existence of shunting of oxygen from arterial to venous segments of the renal capillary bed was ascertained from densitometer tracings of renal venous blood after the injection into the renal artery of blood of high oxygen tension and containing optically labeled erythrocytes. The outer region of the renal cortex was functionally separated from the medulla plus inner cortex by means of regional hypothermia. There was observed no consistent exaggeration or attenuation of the diphasic character of the renal densitometer tracing characteristic of oxygen shunting by cooling either the superficial or deeper zones of the kidney. It is concluded that shunting of oxygen occurs in both the renal cortex and medulla, but the degree to which it occurs in each zone cannot be quantified from the present data.