Microbial enzymes: tools for biotechnological processes.
Microbial enzymes: tools for biotechnological processes.
复制标题
DOI：
10.3390/biom4010117
复制
发表时间：
2014-01-16
期刊：
影响因子：
5.5
通讯作者：
Demain AL
中科院分区：
文献类型：
--
作者：
Adrio JL;Demain AL
微生物酶在工业生物过程的发展中具有重要意义。目前的应用集中在许多不同的市场，包括纸浆和纸张，皮革，洗涤剂和纺织品，制药，化工，食品和饮料，生物燃料，动物饲料和个人护理等。如今，需要新的、改进的或/和更通用的酶，以开发更新颖的、可持续的和经济上有竞争力的生产方法。微生物多样性和现代分子技术，如宏基因组学和基因组学，正在被用来发现新的微生物酶，其催化性能可以通过基于理性，半理性和随机定向进化的不同策略来改进/修饰。大多数工业酶是在细菌和真菌中产生的重组形式。
Microbial enzymes are of great importance in the development of industrial bioprocesses. Current applications are focused on many different markets including pulp and paper, leather, detergents and textiles, pharmaceuticals, chemical, food and beverages, biofuels, animal feed and personal care, among others. Today there is a need for new, improved or/and more versatile enzymes in order to develop more novel, sustainable and economically competitive production processes. Microbial diversity and modern molecular techniques, such as metagenomics and genomics, are being used to discover new microbial enzymes whose catalytic properties can be improved/modified by different strategies based on rational, semi-rational and random directed evolution. Most industrial enzymes are recombinant forms produced in bacteria and fungi.