Anatomical Changes in the Anterior Chamber Volume After Descemet Membrane Endothelial Keratoplasty
Anatomical Changes in the Anterior Chamber Volume After Descemet Membrane Endothelial Keratoplasty
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DOI：
10.1097/ico.0000000000002535
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发表时间：
2021-06-01
期刊：
影响因子：
2.8
通讯作者：
Kato, Naoko
中科院分区：
文献类型：
--
作者：
Onouchi, Hiromi;Hayashi, Takahiko;Kato, Naoko
目的：为了评估在前房的眼睛进行后弹力层角膜内皮移植术（DMEK）的变化，并确定影响这些changes.Methods的因素：这项回顾性研究包括25例患者的25个人工晶状体眼进行DMEK。我们确定了术前和术后的最佳矫正视力、等效球镜（SE）、前房体积（ACV）、前房深度（ACD）、中央角膜厚度（CCT）和巩膜棘角（SSA）值，使用眼前节光学相干断层扫描和虹膜损伤评分和虹膜后粘连评分进行评估。我们将Delta定义为术后1个月时（6-12个月时SE）每个因素从术前到术后值的平均变化率。结果：与术前ACV值（128 ± 28 mm 3）相比，术后ACV值显著增加至155 ± 21 mm 3（P < 0.001）; Delta SE为+1.01 ± 1.09屈光度。Δ ACV与术前ACD（R = 0.643，P < 0.001）和SSA（R = 0.555，P <0.001）呈负相关，与i Δ ACD（R = 0.799，P < 0.001）和Δ SSA（R = 0.608，P < 0.001）呈正相关。Δ CCT、虹膜损伤评分和虹膜后粘连评分与Δ ACV无显著相关性。Δ SE与Δ ACV、Δ ACD和Δ SSA呈正相关（R = 0.680、0.455和0.478; P < 0.001，
Purpose: To evaluate changes in the anterior chamber of eyes that have undergone Descemet membrane endothelial keratoplasty (DMEK) and to identify factors that affect these changes.Methods: This retrospective study included 25 pseudophakic eyes of 25 patients who underwent DMEK. We determined the preoperative and postoperative values of the best spectacle-corrected visual acuity, spherical equivalent (SE), anterior chamber volume (ACV), anterior chamber depth (ACD), central corneal thickness (CCT), and scleral spur angle (SSA) evaluated using anterior segment optical coherence tomography and iris damage score and iris posterior synechiae score. We defined Delta as the average change rate from the preoperative to postoperative value for each factor at 1 month (SE at 6-12 months) postoperatively. We also analyzed correlations between Delta ACV, Delta SE, and other preexisting factors.Results: Compared with the preoperative ACV value (128 +/- 28 mm3), the postoperative value significantly increased to 155 +/- 21 mm3 (P < 0.001); Delta SE was +1.01 +/- 1.09 diopters. Delta ACV was negatively correlated with preoperative ACD (R = 0.643, P < 0.001) and SSA (R = 0.555, P = 0.001) and positively correlated with i Delta ACD (R = 0.799, P < 0.001) and Delta SSA (R = 0.608, P < 0.001). Delta CCT, iris damage score, and iris posterior synechiae score were not significantly correlated with Delta ACV. Delta SE was positively correlated with Delta ACV, Delta ACD, and Delta SSA (R = 0.680, 0.455, and 0.478; P < 0.001,