Duration of anticoagulation for venous thromboembolic events.
Duration of anticoagulation for venous thromboembolic events.
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DOI：
10.1161/circulationaha.114.010456
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发表时间：
2014-12-23
期刊：
影响因子：
37.8
通讯作者：
Berger JS
中科院分区：
文献类型：
--
作者：
Smilowitz NR;Mega JL;Berger JS
一位68岁的女性，有高血压、高脂血症和憩室炎病史，到您的办公室进行随访。三个月前，她的右小腿和大腿出现了3天的疼痛和肿胀。下肢静脉超声检查显示右股静脉深静脉血栓形成。未发现可识别的原因。她开始接受治疗性依诺肝素作为华法林抗凝治疗特发性静脉血栓栓塞症的桥梁。自出院以来，她的国际标准化比值（INR）一直维持在2 - 3之间。她没有既往出血或血栓栓塞事件史。她想知道持续抗凝多久，以及她可以做些什么来最大限度地减少复发性静脉血栓栓塞的风险。
A 68 year-old woman with a history of hypertension, hyperlipidemia, and diverticulitis presents to your office for follow-up care. Three months ago, she developed 3 days of pain and swelling in her right calf and thigh. Lower extremity venous ultrasonography demonstrated a deep vein thrombosis in the right femoral vein. No identifiable cause was noted. She was started on therapeutic enoxaparin as a bridge to warfarin anticoagulation for idiopathic venous thromboembolism. Since discharge, her international normalized ratio (INR) has been maintained between 2 and 3. She has no history of prior bleeding or thromboembolic events. She wants to know how long to continue anticoagulation, and what she can do to minimize her risk of recurrent venous thromboembolism.