Morphology of axon collaterals of single climbing fibers in the deep cerebellar nuclei of the rat
Morphology of axon collaterals of single climbing fibers in the deep cerebellar nuclei of the rat
复制标题
大鼠小脑深部核团单攀爬纤维轴突侧枝的形态
DOI：
10.1016/0304-3940(96)13063-9
复制
发表时间：
1996
影响因子：
2.5
通讯作者：
Y. Shinoda
中科院分区：
文献类型：
--
作者：
I. Sugihara;H. Wu;Y. Shinoda
用注射生物素的葡聚糖胺标记的单个轴突重建大鼠下橄榄核(IO)神经元向小脑深核(CN)的投射。在CN(n=18)，所有重建的末梢分支都是由攀升纤维(CFs)形成的侧支。从皮质终末分支到IO的几乎整个路径向后重建的6个CFs，每一个发出1~6个核侧支。核侧支直径(0.2~0.3μm)比投射到浦肯野细胞的干轴突(0.7~1.4μm)薄得多。单侧核侧支肿胀数为24~118个(n=18)。起源于单个纤维的核侧枝的末端分支扩展到数百微米，并在中央核内占据局部部分。
Projection of inferior olive (IO) neurons to the deep cerebellar nuclei (CN) was investigated in the rat by reconstructing single axons that were labeled with biotinylated dextran amine injected into the IO. All reconstructed terminal arborizations in the CN (n = 18) arose as collaterals from climbing fibers (CFs). One to six nuclear collaterals were given off from each of six CFs that were reconstructed along the nearly entire pathway backward from cortical terminal arborizations to the IO. Nuclear collaterals were much thinner (0.2–0.3 μm in diameter) than stem axons projecting to Purkinje cells (0.7–1.4 μm). The number of swelling per a single nuclear collateral ranged from 24 to 118 (n = 18). Terminal arborizations of nuclear collaterals originating from a single CF spread for some hundreds of micrometers and occupied a localized portion within the CN.