Anterior Segment Optical Coherence Tomography Parameters in Subtypes of Primary Angle Closure
Anterior Segment Optical Coherence Tomography Parameters in Subtypes of Primary Angle Closure
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DOI：
10.1167/iovs.13-12285
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发表时间：
2013-08-01
影响因子：
4.4
通讯作者：
Aung, Tin
中科院分区：
文献类型：
--
作者：
Guzman, Celeste P.;Gong, Tianxia;Aung, Tin
目的：比较通过眼前节光学相干断层扫描（ASOCT）评估的被归类为原发性房角关闭疑似（PACS）、原发性房角关闭（PAC）、原发性闭角型青光眼（PACG）以及既往急性原发性房角关闭（APAC）的受试者的眼前节参数，并确定与APAC相关的因素。
方法：这是一项对425名房角关闭受试者（176名PACS、66名PAC、125名PACG和58名APAC）进行的前瞻性ASOCT研究。使用定制软件测量ASOCT参数，包括房角开放距离（AOD750）、小梁 - 虹膜间隙面积（TISA750）、前房深度、宽度、面积和容积（ACD、ACW、ACA、ACV）、虹膜厚度（IT750）、虹膜面积（IAREA）以及晶状体拱高（LV）。通过对年龄、性别和瞳孔直径（PD）进行调整的协方差分析（ANCOVA）评估眼前节参数的平均差异。
结果：不同亚组之间的比较显示，与其他亚组相比，APAC组的ACD、ACA和ACV最小，IT750最厚（P < 0.001）。LV在APAC组中最大（1218 ± 34μm），其次分别是PAC（860 ± 31μm）、PACG（845 ± 23μm）和PACS（804 ± 19μm）（P =
（最后一个P = 后面似乎内容不完整）
PURPOSE. To compare anterior segment parameters, assessed by anterior segment optical coherence tomography (ASOCT), in subjects categorized as primary angle closure suspect (PACS), primary angle closure (PAC), primary angle closure glaucoma (PACG), and previous acute PAC (APAC); and to identify factors associated with APAC.METHODS. This was a prospective ASOCT study of 425 subjects with angle closure (176 PACS, 66 PAC, 125 PACG, and 58 APAC). Customized software was used to measure ASOCT parameters, including angle opening distance (AOD750), trabecular-iris space area (TISA750), anterior chamber depth, width, area and volume (ACD, ACW, ACA, ACV), iris thickness (IT750), iris area (IAREA), and lens vault (LV). Mean differences in anterior segment parameters were evaluated by analysis of covariance (ANCOVA) adjusted for age, sex, and pupil diameter (PD).RESULTS. Comparison among the different subgroups showed that ACD, ACA, and ACV were smallest, and IT750 thickest in the APAC group compared with the other subgroups (P < 0.001). LV was greatest in the APAC group (1218 +/- 34 mu m) followed by PAC (860 6 31 mu m), PACG (845 +/- 23 mu m), and PACS (804 +/- 19 mu m), respectively (P =